• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

炎症性肠病护理的成本:如何使其可持续发展。

The Cost of Inflammatory Bowel Disease Care: How to Make it Sustainable.

作者信息

Burisch Johan, Claytor Jennifer, Hernandez Inmaculada, Hou Jason Ken, Kaplan Gilaad G

机构信息

Gastro Unit, Medical Division, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark; Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Division of Gastroenterology, Mount Sinai Hospital, New York City, New York.

出版信息

Clin Gastroenterol Hepatol. 2025 Feb;23(3):386-395. doi: 10.1016/j.cgh.2024.06.049. Epub 2024 Aug 14.

DOI:10.1016/j.cgh.2024.06.049
PMID:39151644
Abstract

The rising global prevalence of inflammatory bowel diseases (IBDs), such as Crohn's disease and ulcerative colitis, underscores the need to examine current and future IBD care costs. Direct health care expenses, including ambulatory visits, hospitalizations, and medications, are substantial, averaging $9,000 to $12,000 per person annually in high-income regions. However, these estimates do not fully account for factors such as disease severity, accessibility, and variability in health care infrastructure among regions. Indirect costs, predominantly stemming from loss in productivity due to absenteeism, presenteeism, and other intangible costs, further contribute to the financial burden of IBD. Despite efforts to quantify indirect costs, many aspects remain poorly understood, leading to an underestimation of their actual impact. Challenges to achieving cost sustainability include disparities in access, treatment affordability, and the absence of standardized cost-effective care guidelines. Strategies for making IBD care sustainable include early implementation of biologic therapies, focusing on cost-effectiveness in settings with limited resources, and promoting the uptake of biosimilars to reduce direct costs. Multidisciplinary care teams leveraging technology and patient-reported outcomes also hold promise in reducing both direct and indirect costs associated with IBD. Addressing the increasing financial burden of IBD requires a comprehensive approach that tackles disparities, enhances access to cost-effective therapeutics, and promotes collaborative efforts across health care systems. Embracing innovative strategies can pave the way for personalized, cost-effective care accessible to all individuals with IBD, ensuring better outcomes and sustainability.

摘要

全球范围内,诸如克罗恩病和溃疡性结肠炎等炎症性肠病(IBD)的患病率不断上升,这凸显了审视当前及未来IBD治疗成本的必要性。直接医疗费用,包括门诊就诊、住院治疗和药物费用,数额巨大,在高收入地区人均每年平均为9000美元至12000美元。然而,这些估算并未充分考虑疾病严重程度、可及性以及各地区医疗基础设施差异等因素。间接成本主要源于旷工、出勤但工作效率低下以及其他无形成本导致的生产力损失,这进一步加重了IBD的经济负担。尽管人们努力对间接成本进行量化,但许多方面仍知之甚少,导致对其实际影响估计不足。实现成本可持续性面临的挑战包括医疗服务可及性的差异、治疗费用的可承受性以及缺乏标准化的成本效益护理指南。使IBD治疗具有可持续性的策略包括尽早实施生物疗法、在资源有限的环境中注重成本效益,以及推广生物类似药以降低直接成本。利用技术和患者报告结果的多学科护理团队在降低与IBD相关的直接和间接成本方面也具有前景。应对IBD日益增加的经济负担需要一种全面的方法,解决差异问题、增加获得具有成本效益治疗方法的机会,并促进整个医疗系统的协作努力。采用创新策略可为所有IBD患者提供个性化、具有成本效益的护理铺平道路,确保更好的治疗效果和可持续性。

相似文献

1
The Cost of Inflammatory Bowel Disease Care: How to Make it Sustainable.炎症性肠病护理的成本:如何使其可持续发展。
Clin Gastroenterol Hepatol. 2025 Feb;23(3):386-395. doi: 10.1016/j.cgh.2024.06.049. Epub 2024 Aug 14.
2
The Impact of Inflammatory Bowel Disease in Canada 2018: Direct Costs and Health Services Utilization.2018年炎症性肠病对加拿大的影响:直接成本与医疗服务利用情况
J Can Assoc Gastroenterol. 2019 Feb;2(Suppl 1):S17-S33. doi: 10.1093/jcag/gwy055. Epub 2018 Nov 2.
3
The Impact of Inflammatory Bowel Disease in Canada 2018: Indirect Costs of IBD Care.2018年加拿大炎症性肠病的影响:炎症性肠病护理的间接成本
J Can Assoc Gastroenterol. 2019 Feb;2(Suppl 1):S34-S41. doi: 10.1093/jcag/gwy050. Epub 2018 Nov 2.
4
The Cost of Inflammatory Bowel Disease: An Initiative From the Crohn's & Colitis Foundation.炎症性肠病的成本:来自克罗恩病和结肠炎基金会的倡议。
Inflamm Bowel Dis. 2020 Jan 1;26(1):1-10. doi: 10.1093/ibd/izz104.
5
Economic Burden and Health Care Access for Patients With Inflammatory Bowel Diseases in China: Web-Based Survey Study.中国炎症性肠病患者的经济负担和医疗保健可及性:基于网络的调查研究。
J Med Internet Res. 2021 Jan 5;23(1):e20629. doi: 10.2196/20629.
6
The cost of illness analysis of inflammatory bowel disease.炎症性肠病的疾病经济负担分析。
BMC Gastroenterol. 2023 Jan 19;23(1):21. doi: 10.1186/s12876-023-02648-z.
7
Inflammatory bowel disease: a Canadian burden of illness review.炎症性肠病:加拿大疾病负担综述
Can J Gastroenterol. 2012 Nov;26(11):811-7. doi: 10.1155/2012/984575.
8
Costs of inflammatory bowel disease in Germany.德国炎症性肠病的成本。
Pharmacoeconomics. 2006;24(8):797-814. doi: 10.2165/00019053-200624080-00006.
9
Disease-Associated Costs in Children With Inflammatory Bowel Disease: A Systematic Review.炎症性肠病患儿的疾病相关成本:系统评价。
Inflamm Bowel Dis. 2020 Jan 6;26(2):206-215. doi: 10.1093/ibd/izz120.
10
Inflammatory bowel disease-attributable costs and cost-effective strategies in the United States: a review.美国炎症性肠病相关成本和具有成本效益的策略:综述。
Inflamm Bowel Dis. 2011 Jul;17(7):1603-9. doi: 10.1002/ibd.21488. Epub 2010 Nov 4.

引用本文的文献

1
The global burden of inflammatory bowel disease: from 2025 to 2045.2025年至2045年炎症性肠病的全球负担
Nat Rev Gastroenterol Hepatol. 2025 Jul 18. doi: 10.1038/s41575-025-01097-1.
2
Oxidative Stress, Gut Bacteria, and Microalgae: A Holistic Approach to Manage Inflammatory Bowel Diseases.氧化应激、肠道细菌与微藻:一种管理炎症性肠病的整体方法。
Antioxidants (Basel). 2025 Jun 9;14(6):697. doi: 10.3390/antiox14060697.
3
Prioritizing inflammatory bowel disease.优先考虑炎症性肠病。
Nat Rev Gastroenterol Hepatol. 2025 Jun;22(6):361. doi: 10.1038/s41575-025-01078-4.
4
What do patients and informal caregivers value in IBD care? A narrative inquiry.患者及非正式照护者在炎症性肠病护理中看重什么?一项叙事探究。
BMC Health Serv Res. 2025 May 10;25(1):681. doi: 10.1186/s12913-025-12823-5.
5
Global evolution of inflammatory bowel disease across epidemiologic stages.炎症性肠病在各流行病学阶段的全球演变
Nature. 2025 Apr 30. doi: 10.1038/s41586-025-08940-0.
6
Shaping the future of inflammatory bowel disease: a global research agenda for better management and public health response.塑造炎症性肠病的未来:一份关于改善管理和公共卫生应对的全球研究议程。
Nat Rev Gastroenterol Hepatol. 2025 Apr 22. doi: 10.1038/s41575-025-01063-x.
7
Musculoskeletal Symptoms and Clinical Findings in Bio-naïve Patients with Inflammatory Bowel Disease Prior to Biological Treatment Initiation: A Prospective Cohort Study.生物治疗开始前初治炎症性肠病患者的肌肉骨骼症状及临床发现:一项前瞻性队列研究
Dig Dis Sci. 2025 Apr 15. doi: 10.1007/s10620-025-09016-9.
8
Relapse Rates and Predictors for Relapse in Ulcerative Colitis and Crohn's Disease Patients After Discontinuation of Vedolizumab or Ustekinumab: The REVEUS Study.维多珠单抗或优特克单抗停药后溃疡性结肠炎和克罗恩病患者的复发率及复发预测因素:REVEUS研究
J Clin Med. 2025 Mar 7;14(6):1793. doi: 10.3390/jcm14061793.
9
Paradigm Shift in Inflammatory Bowel Disease Management: Precision Medicine, Artificial Intelligence, and Emerging Therapies.炎症性肠病管理的范式转变:精准医学、人工智能及新兴疗法
J Clin Med. 2025 Feb 25;14(5):1536. doi: 10.3390/jcm14051536.
10
Advanced Combination Therapy with Biologics and Upadacitinib in Refractory Inflammatory Bowel Disease: A Retrospective Study from Taiwan.生物制剂与乌帕替尼联合用于难治性炎症性肠病的高级联合疗法:一项来自台湾的回顾性研究。
J Inflamm Res. 2025 Feb 26;18:2733-2742. doi: 10.2147/JIR.S511309. eCollection 2025.