Yale School of Medicine, Department of Psychiatry, New Haven, CT 06511, United States of America.
Yale School of Medicine, Department of Psychiatry, New Haven, CT 06511, United States of America.
J Subst Use Addict Treat. 2024 Nov;166:209493. doi: 10.1016/j.josat.2024.209493. Epub 2024 Aug 14.
To understand the influence of phenotypic characteristics, such as stress, on substance use treatment outcomes, measures must function equivalently across groups to allow for interpretable comparisons of effects. The present study evaluated measurement invariance of the Perceived Stress Scale (PSS) across race, sex, and time, examined its association with cocaine use disorder (CUD) treatment outcomes, and tested whether associations were moderated by race and/or sex.
Data from four clinical trials evaluating behavioral and/or pharmacological treatments for cocaine use were combined providing a total sample of 302 participants with DSM-IV cocaine abuse/dependence (57.6 % Black, 42.4 % White, 43.7 % females, M = 40.22 years, SD = 9.26).
Factor analyses support a two-factor model (i.e., general stress, self-efficacy to cope with stressors) that demonstrated configural, metric, and scalar invariance across race and sex and configural and metric invariance across time. End-of-treatment stress and coping were both related to treatment outcomes, but not treatment retention. Interactions between baseline and end-of-treatment stress and coping self-efficacy with race and sex predicting treatment retention and outcomes were not significant.
Results support the utility of the PSS to examine between-group differences among individuals with CUD and suggest that sociodemographic groups differ in the extent to which stress and self-efficacy to cope influence treatment outcomes.
为了了解表型特征(如压力)对物质使用治疗结果的影响,必须使测量方法在不同群体中具有等效功能,以便能够对效应进行可解释的比较。本研究评估了感知压力量表(PSS)在种族、性别和时间上的测量不变性,考察了它与可卡因使用障碍(CUD)治疗结果的关系,并检验了种族和/或性别是否调节了这些关系。
来自四项评估可卡因使用行为和/或药物治疗的临床试验的数据被合并,共纳入 302 名符合 DSM-IV 可卡因滥用/依赖标准的参与者(57.6%为黑人,42.4%为白人,43.7%为女性,平均年龄为 40.22 岁,标准差为 9.26)。
因素分析支持一个两因素模型(即一般压力、应对压力源的自我效能),该模型在种族和性别上表现出了结构、度量和标度不变性,在时间上表现出了结构和度量不变性。治疗结束时的压力和应对方式都与治疗结果有关,但与治疗保留率无关。基线和治疗结束时的压力和应对自我效能与种族和性别的交互作用,以及这些交互作用对治疗保留率和结果的预测作用均不显著。
研究结果支持使用 PSS 来检查可卡因使用障碍患者之间的组间差异,并表明社会人口统计学群体在压力和应对自我效能对治疗结果的影响程度上存在差异。