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患者提问,病理学家解答:关于前列腺癌分级的十个问题

Patients ask and pathologists answer: ten questions around prostate cancer grading.

作者信息

Cimadamore Alessia, Cheng Liang, Lopez-Beltran Antonio, Franzese Carmine, Giannarini Gianluca, Crestani Alessandro, Rogers Eamonn T, Montironi Rodolfo

机构信息

Institute of Pathological Anatomy, Department of Medicine, University of Udine, Udine, Italy.

Department of Pathology and Laboratory Medicine, Department of Surgery (Urology), Brown University Warren Alpert Medical School, Lifespan Health, and the Legorreta Cancer Center at Brown University, Providence, RI, USA.

出版信息

Virchows Arch. 2025 May;486(5):1091-1098. doi: 10.1007/s00428-024-03891-9. Epub 2024 Aug 17.

DOI:10.1007/s00428-024-03891-9
PMID:39153109
Abstract

Pathologists have closely collaborated with clinicians, mainly urologists, to update the Gleason grading system to reflect the current practice and approach in prostate cancer diagnosis, prognosis, and treatment. This has led to the development of what is called patient advocacy and patient information. Ten common questions asked by patients to pathologists concerning PCa grading and the answers given by the latter are reported.

摘要

病理学家与临床医生,主要是泌尿科医生密切合作,以更新Gleason分级系统,以反映前列腺癌诊断、预后和治疗方面的当前实践和方法。这促成了所谓的患者宣传和患者信息的发展。本文报告了患者向病理学家提出的关于前列腺癌分级的十个常见问题以及后者给出的答案。

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Patients ask and pathologists answer: ten questions around prostate cancer grading.患者提问,病理学家解答:关于前列腺癌分级的十个问题
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引用本文的文献

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Urologists and pathologists in prostate cancer screening.前列腺癌筛查中的泌尿科医生和病理学家。
Virchows Arch. 2024 Sep 21. doi: 10.1007/s00428-024-03929-y.

本文引用的文献

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Prognosis of Gleason score 8 prostatic adenocarcinoma in needle biopsies: a nationwide population-based study.前列腺针吸活检中 Gleason 评分 8 分前列腺腺癌的预后:一项全国基于人群的研究。
Virchows Arch. 2024 Jun;484(6):995-1003. doi: 10.1007/s00428-024-03810-y. Epub 2024 Apr 29.
2
Using active surveillance for Gleason 7 (3+4) prostate cancer: A narrative review.对 Gleason 7(3+4)前列腺癌采用主动监测:一项叙述性综述。
Can Urol Assoc J. 2024 Apr;18(4):135-144. doi: 10.5489/cuaj.8539.
3
Grade group 4 prostate cancer without intraductal carcinoma on biopsy is more likely to be downgraded on prostatectomy than with intraductal carcinoma.
在前列腺穿刺活检中,若没有导管内癌的 4 级前列腺癌患者,其在前列腺切除术后更有可能降级。
Virchows Arch. 2024 Mar;484(3):517-520. doi: 10.1007/s00428-024-03745-4. Epub 2024 Jan 25.
4
Prognosis of Gleason Score 9-10 Prostatic Adenocarcinoma in Needle Biopsies: A Nationwide Population-based Study.针吸活检中 Gleason 评分 9 - 10 分前列腺腺癌的预后:一项基于全国人口的研究
Eur Urol Oncol. 2024 Apr;7(2):213-221. doi: 10.1016/j.euo.2023.11.002. Epub 2023 Nov 17.
5
Index grade group is superior to composite grade group for prediction of biochemical recurrence following radical prostatectomy.在预测根治性前列腺切除术后的生化复发方面,指数分级组优于综合分级组。
Pathology. 2023 Jun;55(4):492-497. doi: 10.1016/j.pathol.2022.10.012. Epub 2023 Jan 11.
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Renaming Gleason Score 6 Prostate to Noncancer: A Flawed Idea Scientifically and for Patient Care.将 Gleason 评分 6 级前列腺癌重新命名为非癌:一个在科学和患者护理方面都存在缺陷的想法。
J Clin Oncol. 2022 Sep 20;40(27):3106-3109. doi: 10.1200/JCO.22.00926. Epub 2022 Jun 29.
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Low-Grade Prostate Cancer: Time to Stop Calling It Cancer.低级别前列腺癌:是时候不再称其为癌症了。
J Clin Oncol. 2022 Sep 20;40(27):3110-3114. doi: 10.1200/JCO.22.00123. Epub 2022 Apr 18.
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Variance of Tumor Grade at Radical Prostatectomy With Assessment of Each Tumor Nodule Versus Global Grading.前列腺根治性切除术后肿瘤分级的差异:每个肿瘤结节与整体分级的评估。
Arch Pathol Lab Med. 2022 Aug 1;146(8):1032-1036. doi: 10.5858/arpa.2021-0279-OA.
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Genetic Testing Guidelines and Education of Health Care Providers Involved in Prostate Cancer Care.涉及前列腺癌护理的医疗保健提供者的遗传检测指南和教育。
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