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老年创伤重症监护中早期姑息治疗评估后的临床结果。

Clinical Outcomes After Early Palliative Care Evaluations in Geriatric Trauma Intensive Care.

机构信息

Cooper Medical School of Rowan University, Cooper University Health Care, Camden, New Jersey.

Cooper Medical School of Rowan University, Cooper University Health Care, Camden, New Jersey.

出版信息

J Surg Res. 2024 Oct;302:359-363. doi: 10.1016/j.jss.2024.07.062. Epub 2024 Aug 16.

Abstract

INTRODUCTION

Older trauma patients are at risk for worse outcomes compared to younger patients. We hypothesized that early initiation of palliative care (EPC) evaluations, within 72 h of trauma intensive care unit (ICU) admission, would be associated with reduced invasive procedures without a change in hospital mortality.

METHODS

A retrospective cohort review was performed of all trauma patients aged ≥65 y admitted to the trauma (ICU) from January 1, 2016, to December 31, 2021. Patients who received formal palliative care assessments were included. Patient demographics and injury characteristics were evaluated. The primary outcome was ICU length of stay (LOS). Secondary outcomes included code status change, tracheostomy or percutaneous endoscopic gastrostomy placement, use and length of mechanical ventilation, in-hospital mortality, and withdrawal of life-sustaining care.

RESULTS

Two hundred twenty-five patients met inclusion. One hundred and six had EPC while 119 had late palliative care. EPC was associated with decreased ICU LOS (3 versus 9 d, P < 0.001), hospital LOS (3 versus 11 d, P < 0.001), and days on mechanical ventilation (P < 0.001), and fewer tracheostomy (P = 0.007) and percutaneous endoscopic gastrostomy tubes (P = 0.049). There was no difference in withdrawal of life-sustaining care (P = 0.581) or in-hospital mortality (P = 0.172). Pre-existing code status or code status clarification early in admission was associated with EPC (P = 0.003) and decreased interventions.

CONCLUSIONS

EPC is associated with decreased LOS and fewer invasive procedures without a change in hospital mortality. Early discussions regarding code status are helpful in decreasing hospital costs and futile interventions. Further investigation is required to standardize palliative care in this population.

摘要

引言

与年轻患者相比,老年创伤患者的预后更差。我们假设在创伤重症监护病房(ICU)入院后 72 小时内早期启动姑息治疗(EPC)评估,将与减少侵入性操作而不改变住院死亡率相关。

方法

对 2016 年 1 月 1 日至 2021 年 12 月 31 日期间收入创伤 ICU 的所有年龄≥65 岁的创伤患者进行回顾性队列研究。纳入接受正式姑息治疗评估的患者。评估患者的人口统计学和损伤特征。主要结局是 ICU 住院时间(LOS)。次要结局包括代码状态改变、气管切开或经皮内镜胃造口术置管、机械通气的使用和时间、住院死亡率和停止生命支持治疗。

结果

共纳入 225 例患者。106 例患者接受了 EPC,119 例患者接受了晚期姑息治疗。EPC 与 ICU LOS 缩短(3 天 vs. 9 天,P<0.001)、住院 LOS 缩短(3 天 vs. 11 天,P<0.001)和机械通气时间缩短(P<0.001),气管切开术(P=0.007)和经皮内镜胃造口术管(P=0.049)的使用也减少。停止生命支持治疗(P=0.581)或住院死亡率(P=0.172)没有差异。预先存在的代码状态或入院早期代码状态澄清与 EPC(P=0.003)和减少干预措施相关。

结论

EPC 与 LOS 缩短和侵入性操作减少相关,而住院死亡率无变化。早期讨论代码状态有助于降低医院成本和无效干预。需要进一步研究以规范该人群的姑息治疗。

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