Université de Montréal Hospital Research Centre (CRCHUM), Montreal, Quebec, Canada
Department of Social and Preventive Medicine, École de santé publique de l'Université de Montréal, Montreal, Quebec, Canada.
BMJ Open. 2024 Aug 17;14(8):e083425. doi: 10.1136/bmjopen-2023-083425.
To address emerging nutritional epidemiological research questions, data from contemporary cohorts are needed. CARTaGENE is the largest ongoing prospective cohort study of men and women in Québec, Canada. Dietary information was collected making it a rich resource for the exploration of diet in the aetiology of many health outcomes.
CARTaGENE recruited over 43 000 men and women aged 40-69 in two phases (A and B). In phase A, a total of 19 784 men and women were enrolled between 2009 and 2010. In 2011-2012, phase A participants of CARTaGENE were recontacted and invited to complete the self-administered Canadian Diet History Questionnaire II, which assessed usual intake over the past 12 months of a comprehensive array of foods, beverages and supplements; 9379 participants with non-missing age and sex data and with plausible total energy intake comprise the CARTaGENE Cohort Nutrition Study (4212 men; 5167 women).
Available dietary data include intake of total energy, macronutrients and micronutrients, food group equivalents and a measure of diet quality based on the Canadian Healthy Eating Index 2005 (C-HEI 2005). Intake and diet quality varied among participants though they generally met the recommended dietary reference intakes for most nutrients. The mean C-HEI 2005 score was 61.5 (SD=14.0; max score=100), comparable to the general Canadian population. The mean (SD) scores for men and women separately were 57.0 (14.1) and 65.2 (12.8), respectively. C-HEI scores were higher for never smokers (61.6), those who had attained more than a high school education (61.4) and those with high physical activity (60.4) compared with current smokers (55.8), less than high school education level (56.2) and low physical activity (57.6), respectively (p values<0.01).
The CARTaGENE Cohort Nutrition Study is an additional resource of the CARTaGENE platform and is available internationally to examine research questions related to diet and health among contemporary populations. Starting in 2024, annual diet assessments using two 24-hour dietary recalls over a 30-day period will take place, further expanding the cohort as a resource for dietary research.
为了解决新兴的营养流行病学研究问题，需要使用当代队列的数据。CARTaGENE 是加拿大魁北克最大的正在进行的男性和女性前瞻性队列研究。该研究收集了饮食信息，这使其成为探索饮食与许多健康结果病因关系的丰富资源。
CARTaGENE 在两个阶段（A 和 B）共招募了超过 43000 名 40-69 岁的男性和女性。在 A 阶段，2009 年至 2010 年间共招募了 19784 名男性和女性。2011-2012 年，重新联系了 CARTaGENE 的 A 阶段参与者，并邀请他们完成自我管理的加拿大饮食史问卷 II，该问卷评估了过去 12 个月内各种食物、饮料和补品的通常摄入量；共有 9379 名参与者具有非缺失的年龄和性别数据以及合理的总能量摄入，构成了 CARTaGENE 队列营养研究（4212 名男性；5167 名女性）。
可用的饮食数据包括总能量、宏量营养素和微量营养素、食物组当量以及基于加拿大 2005 年健康饮食指数（C-HEI 2005）的饮食质量衡量标准。尽管参与者的饮食摄入和质量存在差异，但他们通常符合大多数营养素的推荐膳食参考摄入量。平均 C-HEI 2005 得分为 61.5（SD=14.0；最大值=100），与加拿大一般人群相当。男性和女性的平均（SD）得分分别为 57.0（14.1）和 65.2（12.8）。与当前吸烟者（55.8）、受教育程度低于高中学历（56.2）和低体力活动（57.6）相比，从不吸烟者（61.6）、受教育程度高于高中学历（61.4）和高体力活动者（60.4）的 C-HEI 得分更高（p 值均<0.01）。
CARTaGENE 队列营养研究是 CARTaGENE 平台的额外资源，可在国际范围内用于研究当代人群饮食与健康相关的研究问题。从 2024 年开始，将进行为期 30 天的两次 24 小时饮食回忆，每年进行一次饮食评估，进一步扩大队列，作为饮食研究的资源。
