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局部麻醉神经阻滞治疗灼口综合征:范围综述。

Local anesthesia nerve block for managing burning mouth syndrome: a scoping review.

机构信息

Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.

Diagnostic Center for Oral Diseases, School of Dentistry, Universidade Federal de Pelotas (UFPel), Pelotas, Rio Grande do Sul, Brazil.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2024 Nov;138(5):619-625. doi: 10.1016/j.oooo.2024.07.007. Epub 2024 Jul 22.

Abstract

OBJECTIVE

To assess the clinical scenarios in which nerve blocks are employed in the context of burning mouth syndrome (BMS).

STUDY DESIGN

This scoping review followed the PRISMA-ScR. A protocol was generated on Open Science Framework. Electronic searches were performed in the following databases: PubMed, Scopus, EMBASE, Web of Science, LILACS, and Cochrane, in addition to the grey literature and citations from Grémeau-Richard et al. (2010).

RESULTS

Nerve blocks were used for treatment purposes in all cases. The mandibular nerve and the stellate ganglion were both blocked in 50% studies, while the maxillary nerve and lingual nerve were blocked in 25% study each. The anesthetics used were lidocaine (50%) and bupivacaine (50%). Relief was generally reported after immediate block, and at a mean follow-up of 4.5 weeks, there was considerable improvement compared to the initial conditions when the mandibular and/or maxillary nerve were targeted.

CONCLUSIONS

The use of nerve blocks has been employed in the treatment of patients with refractory BMS. Clinical studies with standardized methodology are necessary to validate and understand the potential role of mandibular and maxillary nerve block in this setting.

摘要

目的

评估在灼口综合征(BMS)背景下使用神经阻滞的临床情况。

研究设计

本范围综述遵循 PRISMA-ScR 原则。在开放科学框架上生成了一份方案。在以下数据库中进行了电子检索:PubMed、Scopus、EMBASE、Web of Science、LILACS 和 Cochrane,此外还检索了 Gremeau-Richard 等人(2010 年)的灰色文献和参考文献。

结果

神经阻滞在所有情况下均用于治疗目的。50%的研究中阻滞了下颌神经和星状神经节,25%的研究中各阻滞了上颌神经和舌神经。所用的麻醉剂为利多卡因(50%)和布比卡因(50%)。即时阻滞后通常会立即缓解,在平均 4.5 周的随访中,与最初的下颌和/或上颌神经阻滞时相比,情况有了相当大的改善。

结论

在治疗难治性 BMS 患者时已使用神经阻滞。需要采用标准化方法的临床研究来验证和理解下颌和上颌神经阻滞在这种情况下的潜在作用。

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