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利多卡因或利多卡因-布比卡因混合物注入犬眶下管的效果。

The effects of lidocaine or a lidocaine-bupivacaine mixture administered into the infraorbital canal in dogs.

作者信息

Pascoe Peter J

出版信息

Am J Vet Res. 2016 Jul;77(7):682-7. doi: 10.2460/ajvr.77.7.682.

Abstract

OBJECTIVE To determine the onset, duration, and extent of regional nerve blocks performed by administration of lidocaine or lidocaine-bupivacaine into the infraorbital canal in dogs. ANIMALS 6 healthy hound-type dogs. PROCEDURES Under general anesthesia, stimulating needles were inserted into the gingiva dorsolateral to both maxillary canine (MC) teeth and the maxillary fourth premolar (MPM4) and second molar (MM2) teeth on the treatment side. A reflex-evoked muscle potential (REMP) was recorded from the digastricus muscle after noxious electrical stimulation at each site. After baseline measurements, 1 mL of 2% lidocaine solution or a 2% lidocaine-0.5% bupivacaine mixture (0.5 mL each) was injected into the infraorbital canal (at approx two-thirds of the canal length measured rostrocaudally). The REMPs were recorded for up to 7 hours. The REMP data for the contralateral (untreated control) canine tooth were used to normalize results for all stimulation sites. RESULTS With both treatments, nerve block for MC teeth on the treated side was achieved by 5 (n = 5 dogs) or 10 (1) minutes after injection, but nerve block for ipsilateral MPM4 and MM2 teeth was successful for only 3 dogs and 1 dog, respectively. Mean duration of nerve blocks for MC teeth was 120 and 277 minutes following injection of lidocaine and lidocaine-bupivacaine, respectively. CONCLUSIONS AND CLINICAL RELEVANCE Local anesthesia, as performed in this study, successfully blocked innervation of MC teeth, but results for MPM4 and MM2 teeth were inconsistent. This specific technique should not be used during tooth extractions caudal to the MC teeth.

摘要

目的 确定通过向犬眶下管注射利多卡因或利多卡因-布比卡因进行区域神经阻滞的起效时间、持续时间和范围。

动物 6只健康的猎犬型犬。

方法 在全身麻醉下,将刺激针插入治疗侧上颌两侧尖牙(MC)以及上颌第四前磨牙(MPM4)和第二磨牙(MM2)背外侧的牙龈。在每个部位进行有害电刺激后,从二腹肌记录反射诱发肌电位(REMP)。在进行基线测量后,将1 mL 2%利多卡因溶液或2%利多卡因-0.5%布比卡因混合液(各0.5 mL)注入眶下管(在沿头尾方向测量的管长约三分之二处)。记录REMP长达7小时。对侧(未治疗对照)尖牙的REMP数据用于对所有刺激部位的结果进行标准化。

结果 两种治疗方法中,治疗侧MC牙在注射后5(n = 5只犬)或10(1只犬)分钟实现神经阻滞,但同侧MPM4和MM2牙仅分别有3只犬和1只犬成功实现神经阻滞。注射利多卡因和利多卡因-布比卡因后,MC牙神经阻滞的平均持续时间分别为120分钟和277分钟。

结论及临床意义 本研究中所进行的局部麻醉成功阻断了MC牙的神经支配,但MPM4和MM2牙的结果不一致。在拔除MC牙尾侧的牙齿时不应使用这种特定技术。

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