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Do quinolones really augment the antifungal effect of amphotericin B in vitro?

作者信息

Overbeek B P, Rozenberg-Arska M, Verhoef J

出版信息

Drugs Exp Clin Res. 1985;11(11):745-6.

PMID:3915463
Abstract

The minimum inhibitory concentrations (MICs) for amphotericin B and the quinolones norfloxacin and ciprofloxacin against 30 clinical isolates of Candida albicans were determined in various liquid media. Interaction studies were carried out to investigate a possible synergistic action of the quinolones on the antifungal effect of amphotericin B. No interaction between the drugs studied was observed in any of the media used.

摘要

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Fluoroquinolone antimicrobial agents.氟喹诺酮类抗菌剂。
Clin Microbiol Rev. 1989 Oct;2(4):378-424. doi: 10.1128/CMR.2.4.378.