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In-vitro effects of Candida albicans of amphotericin B combined with other antibiotics. Preliminary observations.

作者信息

Anséhn S, Granström S, Höjer H, Nilsson L, Akesson E, Lundin A, Thore A

出版信息

Scand J Infect Dis Suppl. 1976(9):62-6.

PMID:795012
Abstract

The effect of amphotericin B combined with rifampicin or doxycycline on growth, oxygen consumption and ATP levels in cultures of Candida albicans, was studied. Alone, neither rifampicin nor doxycycline--even at high concentrations--affected the growth of the test organism. However, when combined with a concentration of amphotericin B which alone did not affect the growth of C. albicans, a pronounced fungistatic effect was obtained with therapeutically attainable concentrations of the drugs.

摘要

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[In-vitro study of the sensitivity of a strain of Candida albicans to an antibiotic-antimycotic combination (refampicin-amphotericin B)].
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