Partners in Health and Research Development, Centre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Department of Global Health, University of Washington, Seattle, USA.
J Int Assoc Provid AIDS Care. 2024 Jan-Dec;23:23259582241274311. doi: 10.1177/23259582241274311.
HIV self-testing (HIVST) has the potential to reduce barriers associated with clinic-based preexposure prophylaxis (PrEP) delivery. We conducted a substudy nested in a prospective, pilot implementation study evaluating patient-centered differentiated care services. Clients chose either a blood-based or oral fluid HIVST kit at the first refill visit. Data were abstracted from program files and surveys were administered to clients. We purposively sampled a subset of PrEP clients and their providers to participate in in-depth interviews. We surveyed ( = 285). A majority (269/285, 94%) reported HIV risk. Blood-based HIVST was perceived as easy to use (76/140, 54%), and (41/140, 29%) perceived it to be more accurate. Oral fluid-based HIVST was perceived to be easy to use (95/107, 89%), but almost all (106/107, 99%) perceived it as less accurate. HIVST improved privacy, reduced workload, and saved time. HIVST demonstrates the potential to streamline facility-based PrEP care in busy African public health facilities.
HIV 自我检测（HIVST）有可能减少与诊所提供的暴露前预防（PrEP）相关的障碍。我们在一项前瞻性试点实施研究中进行了一项嵌套子研究，该研究评估了以患者为中心的差异化护理服务。客户在第一次复诊时选择血液或唾液 HIVST 试剂盒。数据从项目文件中提取，并对客户进行了调查。我们有目的地抽取了一部分 PrEP 客户及其提供者进行深入访谈。我们对（ = 285）人进行了调查。大多数（269/285，94%）报告了 HIV 风险。76/140（54%）人认为血液 HIVST 使用方便，41/140（29%）人认为它更准确。95/107（89%）人认为唾液 HIVST 使用方便，但几乎所有人（106/107，99%）认为它准确性较低。HIVST 提高了隐私性，减轻了工作量，节省了时间。HIVST 有可能简化繁忙的非洲公共卫生机构的基于设施的 PrEP 护理。
