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面部恶性黑色素瘤的罕见表现:一例报告

A Rare Presentation of Malignant Melanoma of the Face: A Case Report.

作者信息

Palatkar Apurva, Jain Yash V, Babu Manu, Shinde Vinod, Ingale Mayur

机构信息

Department of Otolaryngology, Head and Neck Surgery, Dr. D. Y. Patil Medical College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pune, IND.

出版信息

Cureus. 2024 Jul 18;16(7):e64797. doi: 10.7759/cureus.64797. eCollection 2024 Jul.

DOI:10.7759/cureus.64797
PMID:39156466
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11330291/
Abstract

Melanoma is a malignant neoplasm of melanoblasts, which are the precursors of the melanocytes arising from the neural crest cells. Melanomas can occur at various sites like the skin, eyes, upper esophagus, and meninges due to the migration of neural crest cells. Usually, the prognostic factors are decided based on the Breslow index. This case report describes a 61-year-old female who presented with the complaint of pinkish irregular swelling over the left side of her face for six months. The patient had a surgical resection, and the condition was determined to be invasive melanoma following confirmation by magnetic resonance imaging (MRI) and histological examination. Through our case report, we aim to shed light on the existing protocol for managing malignant melanoma while also exploring new aspects of presentation and multidisciplinary action.

摘要

黑色素瘤是成黑素细胞的恶性肿瘤,而成黑素细胞是源自神经嵴细胞的黑素细胞的前体。由于神经嵴细胞的迁移,黑色素瘤可发生于皮肤、眼睛、食管上段和脑膜等不同部位。通常,预后因素是根据 Breslow 指数来确定的。本病例报告描述了一名 61 岁女性,她因左侧面部出现粉红色不规则肿胀六个月前来就诊。患者接受了手术切除,经磁共振成像(MRI)和组织学检查确诊为浸润性黑色素瘤。通过我们的病例报告,我们旨在阐明现有的恶性黑色素瘤管理方案,同时探索其新的临床表现和多学科治疗方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/000e7ff91311/cureus-0016-00000064797-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/563068adacbb/cureus-0016-00000064797-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/3813eac514b0/cureus-0016-00000064797-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/643e81607633/cureus-0016-00000064797-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/1a42954c66b7/cureus-0016-00000064797-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/000e7ff91311/cureus-0016-00000064797-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/563068adacbb/cureus-0016-00000064797-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/3813eac514b0/cureus-0016-00000064797-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/643e81607633/cureus-0016-00000064797-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/1a42954c66b7/cureus-0016-00000064797-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a52/11330291/000e7ff91311/cureus-0016-00000064797-i05.jpg

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引用本文的文献

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本文引用的文献

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Cutaneous Malignant Melanoma: A Review of Early Diagnosis and Management.皮肤恶性黑色素瘤:早期诊断与治疗综述
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Diagnosis of Cutaneous Melanoma: the Gap Between the Knowledge of General Practitioners and Dermatologists in a Brazilian Population.皮肤黑色素瘤的诊断:巴西人群中全科医生和皮肤科医生知识之间的差距。
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Immunological effects of the anti-programmed death-1 antibody on human peripheral blood mononuclear cells.抗程序性死亡-1抗体对人外周血单个核细胞的免疫效应
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Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial.达拉非尼联合曲美替尼与达拉非尼联合安慰剂治疗 Val600BRAF 突变型黑色素瘤:一项多中心、双盲、III 期随机对照临床试验。
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