Tafese Abenezer Melaku, Adela Amanuel Yegnanew, Kebede Assefa Getachew, Tegegn Aklilu Sinte, Asare Elsabeth Tizazu, Awol Munir
Department of Oncology, Addis Ababa University, Addis Ababa, Ethiopia.
Department of Internal Medicine, University of Gondar, Gondar, Ethiopia.
SAGE Open Med Case Rep. 2024 Aug 16;12:2050313X241269594. doi: 10.1177/2050313X241269594. eCollection 2024.
Thromboembolism is a significant cause of mortality and morbidity in cancer patients. While the link between cancer and venous thrombosis is well known, the recognition of arterial thrombosis as a serious complication of cancer and chemotherapeutic agents is a recent development. One of the chemotherapy agents frequently linked to acute vascular events is cisplatin. We discuss a rare case of cisplatin-related brachial arterial thrombosis in a 50-year-old man who was treated for cholangiocarcinoma with cisplatin and gemcitabine. Although rare, cisplatin-related arterial thrombosis demands careful monitoring, a high index of suspicion, and prompt management to prevent serious complications and mortality.
血栓栓塞是癌症患者死亡和发病的重要原因。虽然癌症与静脉血栓形成之间的联系已广为人知，但动脉血栓形成作为癌症和化疗药物的严重并发症却是最近才被认识到的。经常与急性血管事件相关的化疗药物之一是顺铂。我们讨论了一例罕见的与顺铂相关的肱动脉血栓形成病例，患者为一名50岁男性，因胆管癌接受顺铂和吉西他滨治疗。尽管罕见，但与顺铂相关的动脉血栓形成需要仔细监测、高度怀疑指数以及及时处理，以预防严重并发症和死亡。
