马伐卡坦对主动脉瓣狭窄与梗阻性肥厚型心肌病这一具有挑战性的联合病症的有效性
Usefulness of Mavacamten in the Challenging Association of Aortic Stenosis and Obstructive Hypertrophic Cardiomyopathy.
作者信息
Vanhaecke Pierre, Bohbot Yohann, Di Lena Chloé, Hucleux Emilion, Yemmi Mokrane, Tribouilloy Chistophe
机构信息
Department of Cardiology, Amiens University Hospital, Amiens, France.
UR UPJV 7517, Jules Verne University of Picardie, Amiens, France.
出版信息
JACC Case Rep. 2024 Aug 7;29(15):102430. doi: 10.1016/j.jaccas.2024.102430.
The association of aortic stenosis (AS) and obstructive hypertrophic cardiomyopathy raises questions about AS quantification, the management of left ventricular outflow tract obstruction, and AS treatment. Recently, mavacamten demonstrated its efficacy in reducing left ventricular outflow tract obstruction gradient. This case reports on mavacamten use in this challenging association.
主动脉狭窄（AS）与梗阻性肥厚型心肌病的关联引发了关于AS量化、左心室流出道梗阻的管理以及AS治疗等问题。最近，马伐卡坦证明了其在降低左心室流出道梗阻梯度方面的疗效。本病例报告了马伐卡坦在这种具有挑战性的关联中的应用情况。
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