Wang Wenhui, Zhang Xiyue, Zhang Anke, Yu Han, Kang Xinbao, Wang Cheng, Song Yang, Ni Jiahua, Zheludkevich Mikhail L, Zhang Xiaonong
State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai, China.
College of Biological Science and Medical Engineering, Donghua University, Shanghai, China.
Bioact Mater. 2024 Jul 27;41:371-384. doi: 10.1016/j.bioactmat.2024.07.020. eCollection 2024 Nov.
Improving the comprehensive performance of low alloyed Mg is a significant challenge for biomedical applications. This paper developed a high-performance Mg-Zn alloy with uniform ultrafine grains and nano-precipitates through a straightforward, high-temperature reciprocating equal channel angle extrusion (ECAP) process and researched the microstructure, mechanical property, degradation behaviour, and biocompatibility of the developed alloy. Results showed that the lean Mg-2Zn alloy successfully refined grain to about 1 μm and produced plenty of nano-particles with uniform distribution, providing high comprehensive mechanical properties (YS: 235 MPa, UTS: 267 MPa, EL: 15.6 %). Additionally, Zn-riched nano-particles in the matrix could decrease the Zn aggregation at the corrosion layer-matrix interface and form a dense oxide film, achieving a low degradation rate (0.13 mm/year ). Finally, this work realizes the low alloy content, low cost, and good properties of one biodegradable Mg alloy, which will benefit the promotion of future clinical applications.
提高低合金镁的综合性能对生物医学应用来说是一项重大挑战。本文通过一种简单的高温往复等通道转角挤压(ECAP)工艺开发了一种具有均匀超细晶粒和纳米析出物的高性能镁锌合金,并研究了该合金的微观结构、力学性能、降解行为和生物相容性。结果表明,贫镁-2锌合金成功地将晶粒细化至约1μm,并产生了大量分布均匀的纳米颗粒,具有较高的综合力学性能(屈服强度:235MPa,抗拉强度:267MPa,伸长率:15.6%)。此外,基体中富锌纳米颗粒可减少锌在腐蚀层-基体界面处的聚集,并形成致密氧化膜,实现较低的降解速率(0.13mm/年)。最后,这项工作实现了一种生物可降解镁合金的低合金含量、低成本和良好性能,这将有利于未来临床应用的推广。