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Update on Ketamine.氯胺酮最新情况
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Between Emergency Department Visits: The Role of Harm Reduction Programs in Mitigating the Harms Associated With Injection Drug Use.在急诊就诊之间:减少伤害计划在减轻与注射吸毒相关危害方面的作用。
Ann Emerg Med. 2021 May;77(5):479-492. doi: 10.1016/j.annemergmed.2020.11.008. Epub 2021 Feb 10.
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Ketamine abusers referring to emergency departments in northern Italy: a cross- sectional study.意大利北部急诊科氯胺酮滥用者:一项横断面研究。
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Clinical pattern and prevalence of upper gastrointestinal toxicity in patients abusing ketamine.氯胺酮滥用患者上消化道毒性的临床特征和流行率。
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The epidemiology and patterns of acute and chronic toxicity associated with recreational ketamine use.与娱乐性使用氯胺酮相关的急慢性毒性的流行病学及模式。
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Drug-induced liver injury following a repeated course of ketamine treatment for chronic pain in CRPS type 1 patients: a report of 3 cases.氯胺酮治疗 1 型复杂性区域疼痛综合征慢性疼痛后反复用药导致的药物性肝损伤:3 例报告。
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“K 型痉挛”:一名长期使用氯胺酮患者的复发性腹痛病例报告

"K Cramps," Recurrent Abdominal Pain in a Patient with Chronic Ketamine Use: A Case Report.

作者信息

Avra Tucker, Torres Jesus, Felipe Vasudevan Kumar, Samuels Elizabeth A

机构信息

UCLA David Geffen School of Medicine, Los Angeles, California.

UCLA David Geffen School of Medicine, Department of Emergency Medicine, Los Angeles, California.

出版信息

Clin Pract Cases Emerg Med. 2024 Aug;8(3):277-281. doi: 10.5811/cpcem.19431.

DOI:10.5811/cpcem.19431
PMID:39158249
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11326070/
Abstract

INTRODUCTION

Medical and nonmedical ketamine use is increasing in the United States. This will likely lead to an increase in emergency department (ED) visits in individuals experiencing associated side effects. Physicians will need to be able to effectively recognize and manage ketamine-related complications.

CASE REPORT

A 31-year-old male with a three-year history of inhalational, intramuscular, and intravenous nonmedical ketamine use presented to the ED twice within a week with symptoms of severe atraumatic back pain, abdominal pain, and dyspepsia. A comprehensive workup, including advanced imaging, was unrevealing for identifiable causes, and the patient was discharged with instructions for primary care follow-up for further evaluation. The patient used information shared on Reddit, an online forum and social network, to identify that the cause of his pain was related to chronic ketamine use. Subsequently, upon discontinuation of ketamine, the pain improved in 24 hours. The patient self-navigated to addiction treatment.

CONCLUSION

Emergency physicians should consider sequelae of chronic ketamine use as a possible cause for gastrointestinal and urologic symptoms in the ED. In addition to thorough examination and assessment for other acute medical problems, patients should be offered education, symptomatic treatment, and linkage to harm reduction and substance use disorder treatment services.

摘要

引言

在美国,医用和非医用氯胺酮的使用正在增加。这可能会导致出现相关副作用的个体前往急诊科就诊的人数增加。医生将需要能够有效识别和处理与氯胺酮相关的并发症。

病例报告

一名31岁男性,有三年吸入、肌肉注射和静脉注射非医用氯胺酮的病史,在一周内两次前往急诊科,出现严重的非创伤性背痛、腹痛和消化不良症状。包括高级影像学检查在内的全面检查未发现可识别的病因,患者出院时被告知进行初级保健随访以作进一步评估。患者利用在线论坛和社交网络Reddit上分享的信息,确定其疼痛原因与长期使用氯胺酮有关。随后,停用氯胺酮后,疼痛在24小时内有所改善。患者自行寻求成瘾治疗。

结论

急诊科医生应将长期使用氯胺酮的后遗症视为急诊科胃肠道和泌尿系统症状的可能原因。除了对其他急性医疗问题进行全面检查和评估外,还应向患者提供教育、对症治疗,并将其转介至减少伤害和物质使用障碍治疗服务机构。