Croydon Health Services NHS Trust, United Kingdom.
Croydon Health Services NHS Trust, United Kingdom.
Clin Med (Lond). 2024 Sep;24(5):100235. doi: 10.1016/j.clinme.2024.100235. Epub 2024 Aug 17.
Pancytopenia is an uncommon abnormality detected on a full blood count. Features of presentation tend to be non-specific, and are due to impaired functions of the cell lines involved. These can include fatigue, infection and bleeding. However, the aetiology of pancytopenia is extensive. This narrative review aims to provide a minimally invasive diagnostic algorithm for generalist clinicians to approach pancytopenia, including investigations into the underlying aetiology, and when a referral to the haematologist is warranted for further investigations such as bone marrow aspiration and trephine biopsy.
全血细胞计数通常能检测到的一种不常见的异常情况。其表现特征往往不具有特异性，这是由于受影响的细胞系功能受损所致。这些功能障碍可能包括疲劳、感染和出血。然而，导致全血细胞减少的病因广泛。本综述旨在为普通临床医生提供一种微创性诊断算法，用于处理全血细胞减少症，包括对潜在病因的检查，以及何时需要转介血液科医生进行进一步检查，如骨髓抽吸和活检。
