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肠病相关性支气管扩张合并慢性鼻窦炎 1 例报告

Bronchiectasis combined with chronic sinusitis following Celiac disease: a case report.

机构信息

Faculty of Medicine, Damascus University, Damascus, Syria.

出版信息

J Med Case Rep. 2024 Aug 20;18(1):382. doi: 10.1186/s13256-024-04696-9.

Abstract

INTRODUCTION

Celiac disease is a disease triggered by a protein called gluten. Celiac disease has intestinal and extraintestinal manifestations. Bronchiectasis is a permanent dilation of the bronchi that causes symptoms, such as cough producing a large amount of sputum, recurrent respiratory infections, and breathlessness. In addition, bronchiectasis can present in 60% of cases with chronic rhinosinusitis.

CASE PRESENTATION

A 40-year-old Arab woman presented with a worsening old cough with an increased amount of sputum; the patient was diagnosed with Celiac disease 7 months prior. Investigations started with laboratory tests followed by a computed tomography scan for the head and chest, bronchoscopy, bronchoalveolar lavage, and spirometry; the final diagnosis was bronchiectasis with chronic rhinosinusitis. She was advised to commit to the gluten-free diet, in addition to the medications prescribed for her bronchiectasis and chronic rhinosinusitis.

CONCLUSION

Celiac disease and bronchiectasis might share an immunologic disturbance that caused both entities, so Celiac disease should be kept in mind as an etiology for pulmonary diseases.

摘要

介绍

乳糜泻是一种由称为麸质的蛋白质引发的疾病。乳糜泻有肠道和肠道外表现。支气管扩张症是一种导致症状的支气管永久性扩张,如咳嗽产生大量痰、反复呼吸道感染和呼吸困难。此外,支气管扩张症可在 60%的慢性鼻-鼻窦炎病例中出现。

病例介绍

一名 40 岁的阿拉伯女性因旧咳嗽加重且痰量增加而就诊;该患者在 7 个月前被诊断为乳糜泻。检查从实验室检查开始,然后进行头部和胸部 CT 扫描、支气管镜检查、支气管肺泡灌洗和肺功能检查;最终诊断为支气管扩张症伴慢性鼻-鼻窦炎。建议她坚持无麸质饮食,同时服用为她的支气管扩张症和慢性鼻-鼻窦炎开的药物。

结论

乳糜泻和支气管扩张症可能具有导致这两种疾病的免疫紊乱,因此应将乳糜泻视为肺部疾病的病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1f2/11334302/8f9bfc6fc0e0/13256_2024_4696_Fig1_HTML.jpg

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