Mahadeva R, Flower C, Shneerson J
Department of Chest Medicine, West Suffolk Hospital, Edmunds, UK.
Thorax. 1998 Jun;53(6):527-9. doi: 10.1136/thx.53.6.527.
A 48 year old woman presented with a history of fatigue, regular sputum production, and wheeze. High resolution computed tomographic scanning of the thorax demonstrated widespread bronchiectasis. Coeliac disease was diagnosed on the basis of an iron deficiency anaemia, subtotal villous atrophy on small bowel biopsy, and raised anti-gliadin and antiendomysial antibodies. The temporal relationship of the bronchiectasis and coeliac disease, and the subsequent stabilisation of her clinical symptoms and improvement in pulmonary physiology following treatment with inhaled corticosteroids, suggests a relationship between the two conditions which may be due to immunological mechanisms.
一名48岁女性,有疲劳、咳痰及喘息病史。胸部高分辨率计算机断层扫描显示广泛支气管扩张。根据缺铁性贫血、小肠活检显示绒毛部分萎缩以及抗麦胶蛋白和抗肌内膜抗体升高,诊断为乳糜泻。支气管扩张与乳糜泻的时间关系,以及吸入糖皮质激素治疗后临床症状的稳定和肺功能的改善,提示这两种疾病之间可能存在免疫机制介导的关系。