A Case Study of Severe Pneumonia Caused by mixed Infection of and in a Female Patient.

BACKGROUND

is a zoonotic pathogen that causes miscarriage, stillbirth, and sepsis of pregnancy in pregnant women when it infects humans. However, it rarely causes pneumonia in humans.

CASE PRESENTATION

This case reports a case of severe pneumonia characterized by high fever and cough, and the disease rapidly progressed to dyspnea. The patient was treated with moxifloxacin and doxycycline. detected in bronchoscopy examination and bronchoalveolar lavage fluid (BALF) through metagenomic next-generation sequencing (mNGS)-DNA. A weak positive for () antigen was also found in the throat swab tested. Subsequently, we added mabaloxavir and replaced doxycycline with an intravenous infusion of omadacycline. After effective treatment, the patient developed a urinary tract infection, and the treatment plan was adjusted to meropenem combined with omadacycline. The patient's condition improved, and she was discharged on the 14th day of admission.

CONCLUSION

This is the first report of cases of non-pregnant female patients with infection pneumonia. Consequently, infections with can result in severe respiratory distress, disturbance of water and electrolyte balance, and abnormal liver function, which requires timely diagnosis and correct use of antibiotics by clinicians. Consequently, the mixed infection of and aggravated the complexity of the condition and treatment. Combining tetracycline and quinolone is effective for treating severe pneumonia with infection.