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以肺部罕见肿块为表现的肺朗格汉斯细胞组织细胞增多症：1例罕见病例报告及文献复习

Pulmonary Langerhans cell histiocytosis presenting as an uncommon mass in the lung: A rare case report and literature review.

作者信息

Zhang Tingxiu, Hu Sheng, Teng Yue, Li Zhiwei, Xiao Zhenliang, Ma Lijie

机构信息

Department of Pulmonary and Critical Care Medicine Chinese People's Liberation Army Western Theater General Hospital Chengdu Sichuan China.

出版信息

Clin Case Rep. 2024 Aug 19;12(8):e9342. doi: 10.1002/ccr3.9342. eCollection 2024 Aug.

DOI:10.1002/ccr3.9342
PMID:39161669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11331026/
Abstract

A comprehensive diagnostic approach, including immunohistochemistry, is crucial for confirming pulmonary Langerhans cell histiocytosis in adults. Individualized treatment with dynamically adjusted chemotherapy based on therapeutic response leads to significant absorption of lesions and symptom alleviation. Regular follow-up and timely treatment adjustments according to the patient's condition are essential in managing this rare disease.

摘要

包括免疫组织化学在内的综合诊断方法对于确诊成人肺朗格汉斯细胞组织细胞增多症至关重要。基于治疗反应动态调整化疗方案的个体化治疗可使病灶显著吸收并缓解症状。对于这种罕见疾病的管理，定期随访并根据患者病情及时调整治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/e88cd380a2f5/CCR3-12-e9342-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/2e825ab26a9a/CCR3-12-e9342-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/9d85e8321024/CCR3-12-e9342-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/1f1e51a42287/CCR3-12-e9342-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/8ed59e500121/CCR3-12-e9342-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/e88cd380a2f5/CCR3-12-e9342-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/2e825ab26a9a/CCR3-12-e9342-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/9d85e8321024/CCR3-12-e9342-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/1f1e51a42287/CCR3-12-e9342-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/8ed59e500121/CCR3-12-e9342-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11331026/e88cd380a2f5/CCR3-12-e9342-g001.jpg

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本文引用的文献

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Solitary Involvement of the Liver: A Rare Manifestation of Langerhans Cell Histiocytosis.肝脏单发累及：朗格汉斯细胞组织细胞增生症的一种罕见表现。
Am J Case Rep. 2022 Nov 21;23:e937628. doi: 10.12659/AJCR.937628.
2
Insidious Onset of Pulmonary Langerhans Cell Histiocytosis During Oncological Follow-Up.肿瘤随访期间肺朗格汉斯细胞组织细胞增多症的隐匿性起病
J Belg Soc Radiol. 2022 Oct 20;106(1):96. doi: 10.5334/jbsr.2913. eCollection 2022.
3
Two smoking-related lesions in the same pulmonary lobe of squamous cell carcinoma and pulmonary Langerhans cell histiocytosis: A case report.
同一肺叶内鳞状细胞癌与肺朗格汉斯细胞组织细胞增多症的两种吸烟相关病变：病例报告
World J Clin Cases. 2022 Jul 6;10(19):6722-6727. doi: 10.12998/wjcc.v10.i19.6722.
4
Clinical analysis for 15 patients with pulmonary Langerhans cell histiocytosis and literature review.15 例肺朗格汉斯细胞组织细胞增生症临床分析并文献复习
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 Mar 28;47(3):334-343. doi: 10.11817/j.issn.1672-7347.2022.210581.
5
Limited Utility of Chemotherapy for Pulmonary Langerhans Cell Histiocytosis Due to Unclear Diagnostic Criteria.由于诊断标准不明确，化疗对肺朗格汉斯细胞组织细胞增多症的效用有限。
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