Kaneko Umihiko, Hachinohe Daisuke, Kobayashi Ken, Shitan Hidemasa, Horita Ryo, Ootake Ryo, Fujita Tsutomu
Department of Cardiovascular Medicine, Sapporo Cardio Vascular Clinic, North 49, East 16, 8-1 Higashi Ward, Sapporo, Hokkaido 007-0849, Japan.
Eur Heart J Case Rep. 2024 Aug 7;8(8):ytae405. doi: 10.1093/ehjcr/ytae405. eCollection 2024 Aug.
Severely calcified aortic valves are a major limitation of transcatheter aortic valve replacement, because eccentric and heavy calcification of the aortic valve occasionally inhibits self-expansion of the valve frame, resulting in stent under-expansion, including non-uniform expansion or infolding. Nevertheless, the two-dimensional nature of fluoroscopic projection imaging can limit detection of stent under-expansion prior to the final release.
We present two cases demonstrating the importance of the steep right anterior oblique (RAO) view (>50°) in detecting significant stent under-expansion of a self-expanding valve prior to the final release. In Case 1, despite enough pre-dilatation, the partially deployed transcatheter heart valve (THV) appeared to be a substantial under-expansion, which was detected only in steep RAO view. Immediately after the final release, the THV was spontaneously embolized into the ascending aorta (the so-called 'pop-up' phenomenon). Emergent implantation of balloon-expandable valve proved to be successful as a bailout. In Case 2, significant stent distortion and infolding, especially on the non-coronary cusp side, was successfully diagnosed only in a steep RAO view prior to the final release. This finding allowed THV recapture and replacement with a new THV.
Notably, the steep RAO view can visualize the THV from its short axis while eliminating parallax, allowing for accurate diagnosis of THV under-expansion particularly in patients with severe calcification in the non- or right-coronary cusp. Therefore, the steep RAO view allows timely detection of THV under-expansion before the final release, enabling THV recapture and the adoption of several management strategies.
严重钙化的主动脉瓣是经导管主动脉瓣置换术的主要限制因素,因为主动脉瓣的偏心和重度钙化有时会抑制瓣膜支架的自膨胀,导致支架扩张不足,包括扩张不均匀或内折。然而,透视投影成像的二维特性可能会限制在最终释放前对支架扩张不足的检测。
我们展示了两例病例,证明了在最终释放前,陡峭右前斜位(RAO)视图(>50°)对于检测自膨胀瓣膜显著支架扩张不足的重要性。在病例1中,尽管进行了充分的预扩张,但部分展开的经导管心脏瓣膜(THV)似乎存在明显的扩张不足,仅在陡峭RAO视图中被检测到。最终释放后,THV立即自发栓塞至升主动脉(即所谓的“弹出”现象)。紧急植入球囊扩张瓣膜作为补救措施取得成功。在病例2中,仅在最终释放前的陡峭RAO视图中成功诊断出显著的支架变形和内折,尤其是在无冠瓣一侧。这一发现使得能够回收THV并用新的THV进行置换。
值得注意的是,陡峭RAO视图可以从短轴方向观察THV,同时消除视差,从而能够准确诊断THV扩张不足,特别是在无冠瓣或右冠瓣严重钙化的患者中。因此,陡峭RAO视图能够在最终释放前及时检测到THV扩张不足,从而实现THV回收并采取多种管理策略。