Hameau Rene, Ancona Marco B, Romano Vittorio, Ferri Luca, Bellini Barbara, Russo Filippo, Vella Ciro, Papageorgiu Christos, Napoli Francesca, Licciardi Marco, Ricchetti Gianluca, Tripoli Andrea, Sabarese Rocco, Zaccaria Lorenzo, Montorfano Matteo
Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Unidad de Medicina Cardiovascular Integrada, Hospital Las Higueras, Talcahuano 426000, Chile.
J Cardiovasc Dev Dis. 2025 Jun 7;12(6):215. doi: 10.3390/jcdd12060215.
Underexpansion of a self-expanding transcatheter aortic valve (TAVI) is a critical issue that can negatively impact long-term outcomes, including paravalvular leak, valve thrombosis, and increased mortality. This paper provides a comprehensive review of the pathophysiology and consequences of such complications, including three primary mechanisms: (1) infolding, (2) incorrect site of crossing and (3) true underexpansion. It also discusses strategies to address these challenges, including pre-procedural planning and procedural techniques to ensure proper valve deployment and expansion. Mitigating these issues is essential to improving both immediate and long-term outcomes in TAVI patients.
自膨胀经导管主动脉瓣(TAVI)扩张不足是一个关键问题,会对长期预后产生负面影响,包括瓣周漏、瓣膜血栓形成和死亡率增加。本文全面综述了此类并发症的病理生理学及后果,包括三种主要机制:(1)折叠;(2)跨瓣位点错误;(3)真正的扩张不足。本文还讨论了应对这些挑战的策略,包括术前规划和手术技术,以确保瓣膜正确植入和扩张。减轻这些问题对于改善TAVI患者的近期和长期预后至关重要。