Lin Zian, Chen Siyu, Su Lixian, Cao He, Chen Hongbiao, Fang Yuan, Liang Xue, Chen Jianan, Luo Biyun, Wu Chuanan, Wang Zixin
Shenzhen Longhua District Maternity and Child Healthcare Hospital, Shenzhen, China.
Centre for Health Behaviours Research, JC School of Public Health and Primary Care, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong SAR, China.
Vaccine X. 2024 Jul 20;19:100529. doi: 10.1016/j.jvacx.2024.100529. eCollection 2024 Aug.
China started to implement the HPV vaccination program for females in 2016. This study investigated associations between mothers' decisional conflicts, satisfaction with governmental health promotion materials, and their daughters' HPV vaccination uptake.
A cross-sectional online survey was conducted between July and October 2023 among mothers of girls aged 9-17 years in Shenzhen, China. Participants were mothers having a daughter aged 9-17 years at the survey date and a smartphone with internet access. About 3 % of all primary and secondary schools in Shenzhen were randomly selected by the research team (11 primary schools and 13 secondary schools). Teachers at the selected schools invited mothers of female students aged 9-17 years to complete an anonymous online questionnaire. Multivariate logistic regression was fitted.
Among 11,728 mothers who completed the survey, 18.9% of their index daughters received at least one dose of HPV vaccination. In multivariate analysis, less decisional conflict about the choice of HPV vaccines for their daughters (AOR: 1.07, 95%CI: 1.05, 1.10), more satisfaction with the government's health promotional materials related to HPV vaccines (AOR: 1.15, 95%CI: 1.12, 1.19), receiving more cue to action from significant others (AOR: 1.23, 95%CI: 1.19, 1.27), and perceived higher self-efficacy related to HPV vaccines (AOR: 1.79, 95%CI: 1.67, 1.92) were associated with a higher uptake of HPV vaccines. Perceived susceptibility to HPV (AOR: 0.79, 95%CI: 0.74, 0.85), perceived barriers to having the index daughter receive HPV vaccines (AOR: 0.82, 95%CI: 0.80, 0.84), and mothers who were hesitant to receive HPV vaccination (AOR: 0.75, 95%CI: 0.68, 0.84) were associated with a lower uptake.
HPV vaccination uptake was low among girls in China. Future health promotion should address mothers' decisional conflicts about the choice of HPV vaccines for their daughters and improve the health promotional materials. School-based HPV vaccination programs might be useful.
中国于2016年开始为女性实施人乳头瘤病毒（HPV）疫苗接种计划。本研究调查了母亲的决策冲突、对政府健康促进材料的满意度与女儿HPV疫苗接种率之间的关联。
2023年7月至10月，在中国深圳对9至17岁女孩的母亲进行了一项横断面在线调查。参与者为在调查日期有一名9至17岁女儿且拥有可上网智能手机的母亲。研究团队从深圳所有中小学中随机抽取了约3%（11所小学和13所中学）。所选学校的教师邀请9至17岁女学生的母亲完成一份匿名在线问卷。进行了多变量逻辑回归分析。
在完成调查的11728名母亲中，其指标女儿中有18.9%至少接种了一剂HPV疫苗。在多变量分析中，女儿HPV疫苗选择方面的决策冲突较少（比值比[AOR]：1.07，95%置信区间[CI]：1.05，1.10）、对政府HPV疫苗相关健康促进材料的满意度较高（AOR：1.15，95%CI：1.12，1.19）、从重要他人处获得更多行动提示（AOR：1.23，95%CI：1.19，1.27）以及与HPV疫苗相关的自我效能感较高（AOR：1.79，95%CI：1.67，1.92）与更高的HPV疫苗接种率相关。对HPV的易感性感知（AOR：0.79，95%CI：0.74，0.85）、指标女儿接种HPV疫苗的感知障碍（AOR：0.82，95%CI：0.80，0.84）以及对HPV疫苗接种犹豫不决的母亲（AOR：0.75，95%CI：0.68，0.84）与较低的接种率相关。
中国女孩的HPV疫苗接种率较低。未来的健康促进应解决母亲在为女儿选择HPV疫苗方面的决策冲突，并改进健康促进材料。基于学校的HPV疫苗接种计划可能会有所帮助。
