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2
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Lancet Infect Dis. 2024 Mar;24(3):308-318. doi: 10.1016/S1473-3099(23)00572-8. Epub 2023 Dec 4.
2
The 15-valent pneumococcal conjugate vaccine V114 induces cross-reactive antibodies against pneumococcal serotype 6C.15 价肺炎球菌结合疫苗 V114 可诱导针对肺炎球菌血清型 6C 的交叉反应性抗体。
Hum Vaccin Immunother. 2023 Aug 1;19(2):2235238. doi: 10.1080/21645515.2023.2235238.
3
Novel pneumococcal capsule type 33E results from the inactivation of glycosyltransferase WciE in vaccine type 33F.新型肺炎球菌荚膜型 33E 是由于疫苗型 33F 中的糖基转移酶 WciE 失活而产生的。
J Biol Chem. 2023 Sep;299(9):105085. doi: 10.1016/j.jbc.2023.105085. Epub 2023 Jul 24.
4
PneumoKITy: A fast, flexible, specific, and sensitive tool for serotype screening and mixed serotype detection from genome sequence data.PneumoKITy：一种快速、灵活、特异且敏感的工具，可用于从基因组序列数据中进行血清型筛选和混合血清型检测。
Microb Genom. 2022 Dec;8(12). doi: 10.1099/mgen.0.000904.
5
Potentiating pneumococcal glycoconjugate vaccine PCV13 with saponin adjuvant VSA-1.用皂苷佐剂 VSA-1 增强肺炎球菌多糖结合疫苗 PCV13
Front Immunol. 2022 Dec 12;13:1079047. doi: 10.3389/fimmu.2022.1079047. eCollection 2022.
6
Structural, Genetic, and Serological Elucidation of Streptococcus pneumoniae Serogroup 24 Serotypes: Discovery of a New Serotype, 24C, with a Variable Capsule Structure.结构、遗传和血清学阐明肺炎链球菌 24 血清型：发现一种新的血清型 24C，其荚膜结构具有可变性。
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为多重调理吞噬杀伤试验优化的36株菌株的基因组序列。

Genome sequences of 36 strains optimized for the multiplexed opsonophagocytosis killing assay.

作者信息

Graffice Emma, Meewes Chloe, Ganaie Feroze A, Nahm Moon H, Calix Juan J

机构信息

1Department of Medicine, Division of Infectious Disease, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Division of Pulmonary/Allergy/Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.

出版信息

Microbiol Resour Announc. 2024 Sep 10;13(9):e0055324. doi: 10.1128/mra.00553-24. Epub 2024 Aug 20.

DOI:10.1128/mra.00553-24
PMID:39162469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11385719/
Abstract

A multiplexed opsonophagocytosis assay (MOPA) was developed as a cost-effective, high-throughput biological assay to evaluate the efficacy of pneumococcal vaccines by measurement of opsonophagocytic activity of anti-capsular antibodies. Here, we report draft genomes of the 36 strains of developed for use in the reference pneumococcal MOPA.

摘要

一种多重调理吞噬作用测定法（MOPA）被开发出来，作为一种经济高效的高通量生物学测定法，通过测量抗荚膜抗体的调理吞噬活性来评估肺炎球菌疫苗的效力。在此，我们报告了为用于参考肺炎球菌MOPA而开发的36株菌株的基因组草图。