影响范围：多微生物共生伙伴关系在慢性感染研究中的作用。
mSphere of Influence: The power of polymicrobial partnerships in chronic infection research.
机构信息
Department of Genetics, University of Georgia, Athens, Georgia, USA.
出版信息
mSphere. 2024 Sep 25;9(9):e0043424. doi: 10.1128/msphere.00434-24. Epub 2024 Aug 20.
Abstract
Chelsey VanDrisse works in the field of microbial physiology, studying how acylation of small molecules and proteins affects the development of biofilms. In this mSphere of Influence article, she reflects on the paper "Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system" by Jean-Pierre et al. This paper prompted her to reassess her approach to studying antibiotic tolerance and her design of experiments that search for disease-relevant mutants and phenotypes in the laboratory.
摘要
切尔西·范德里丝从事微生物生理学领域的工作，研究小分子和蛋白质的酰化如何影响生物膜的发育。在本期《mSphere 影响力》文章中，她对让·皮埃尔等人发表的论文“社区组成塑造囊性纤维化多微生物模型系统中微生物特异性表型”进行了反思。这篇论文促使她重新评估自己研究抗生素耐药性的方法，以及她在实验室中寻找与疾病相关的突变体和表型的实验设计。
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Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system.社区组成塑造囊性纤维化多微生物模型系统中微生物特异性表型。
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