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本文引用的文献

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Help, hinder, hide and harm: what can we learn from the interactions between and during respiratory infections?帮助、阻碍、隐藏和伤害:我们能从 和 在呼吸道感染中的相互作用中学到什么?
Thorax. 2019 Jul;74(7):684-692. doi: 10.1136/thoraxjnl-2018-212616. Epub 2019 Feb 18.
2
Analysis of Lung Microbiota in Bronchoalveolar Lavage, Protected Brush and Sputum Samples from Subjects with Mild-To-Moderate Cystic Fibrosis Lung Disease.对轻至中度囊性纤维化肺病患者支气管肺泡灌洗、保护性毛刷和痰液样本中肺部微生物群的分析。
PLoS One. 2016 Mar 4;11(3):e0149998. doi: 10.1371/journal.pone.0149998. eCollection 2016.
3
The biogeography of polymicrobial infection.多重微生物感染的生物地理学。
Nat Rev Microbiol. 2016 Feb;14(2):93-105. doi: 10.1038/nrmicro.2015.8. Epub 2015 Dec 30.
4
Respiratory microbiota resistance and resilience to pulmonary exacerbation and subsequent antimicrobial intervention.呼吸道微生物群对肺部加重及后续抗菌干预的耐药性和恢复力。
ISME J. 2016 May;10(5):1081-91. doi: 10.1038/ismej.2015.198. Epub 2015 Nov 10.
5
Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs.区域隔离驱动囊性纤维化肺部内的细菌多样化。
Cell Host Microbe. 2015 Sep 9;18(3):307-19. doi: 10.1016/j.chom.2015.07.006. Epub 2015 Aug 20.
6
Rapid Detection of Emerging Pathogens and Loss of Microbial Diversity Associated with Severe Lung Disease in Cystic Fibrosis.快速检测与囊性纤维化严重肺部疾病相关的新出现病原体及微生物多样性丧失
J Clin Microbiol. 2015 Jul;53(7):2022-9. doi: 10.1128/JCM.00432-15. Epub 2015 Apr 15.
7
Directly sampling the lung of a young child with cystic fibrosis reveals diverse microbiota.直接对患有囊性纤维化的幼儿肺部进行采样,揭示了多样化的微生物群。
Ann Am Thorac Soc. 2014 Sep;11(7):1049-55. doi: 10.1513/AnnalsATS.201311-383OC.
8
Unique microbial communities persist in individual cystic fibrosis patients throughout a clinical exacerbation.在临床恶化过程中,独特的微生物群落存在于个体囊性纤维化患者中。
Microbiome. 2013 Nov 1;1(1):27. doi: 10.1186/2049-2618-1-27.
9
The adult cystic fibrosis airway microbiota is stable over time and infection type, and highly resilient to antibiotic treatment of exacerbations.成人囊性纤维化气道微生物群随时间和感染类型保持稳定,并且对加重期的抗生素治疗具有高度弹性。
PLoS One. 2012;7(9):e45001. doi: 10.1371/journal.pone.0045001. Epub 2012 Sep 26.
10
Decade-long bacterial community dynamics in cystic fibrosis airways.囊性纤维化气道中长达十年的细菌群落动态。
Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5809-14. doi: 10.1073/pnas.1120577109. Epub 2012 Mar 26.

影响范围:一个用于研究社区的社区。

mSphere of Influence: a Community To Study Communities.

机构信息

Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA

出版信息

mSphere. 2020 Feb 5;5(1):e00047-20. doi: 10.1128/mSphere.00047-20.

DOI:10.1128/mSphere.00047-20
PMID:32024707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7002304/
Abstract

Dominique Limoli studies polymicrobial interactions during cystic fibrosis respiratory disease. In this mSphere of Influence article, she reflects on how two papers (D. A. Hogan, S. D. Willger, E. L. Dolben, T. H. Hampton, et al., PLoS One 11:e0149998, 2016, https://doi.org/10.1371/journal.pone.0149998, and P. Jorth, B. J. Staudinger, X. Wu, K. B. Hisert, et al., Cell Host & Microbe 18:307-319, 2015, https://doi.org/10.1016/j.chom.2015.07.006) have influenced her thinking and research direction, which aims to understand interspecies bacterial communication during airway infections. These studies highlighted for her a need for new perspectives on the pathology of chronic infections in order to improve interventions.

摘要

多米尼克·利莫利研究囊性纤维化呼吸道疾病期间的多微生物相互作用。在这篇《mSphere》的影响力文章中,她反思了两篇论文(D. A. 霍根、S. D. 威格、E. L. 多尔本、T. H. 汉普顿等人,《公共科学图书馆·综合》11 卷,e0149998,2016 年,https://doi.org/10.1371/journal.pone.0149998,以及 P. 乔思、B. J. 斯塔丁格、X. 吴、K. B. 希泽特等人,《细胞宿主与微生物》18 卷,307-319 页,2015 年,https://doi.org/10.1016/j.chom.2015.07.006)如何影响她的思维和研究方向,她的研究旨在了解气道感染期间种间细菌通讯,以期改进干预措施。这些研究使她认识到,需要从新的角度看待慢性感染的病理学,以便改善干预措施。