Liao Meixia, Wu Hongyan, Yang Zhihao, Huang Yan, Janssen Mathieu F, Bonsel Gouke, Luo Nan
Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, #10-01, Singapore, 117549, Singapore.
School of Medicine and Health Management, Guizhou Medical University, Guiyang, China.
Eur J Health Econ. 2025 Apr;26(3):403-411. doi: 10.1007/s10198-024-01714-x. Epub 2024 Aug 9.
This study aimed to evaluate the psychometric properties of four candidate cognition bolt-on items and their combinations to the EQ-5D-5L.
Four cognition items (concentration, memory, calculation, and learning) were developed as separate questionnaire items, and were administered with the standard EQ-5D-5L to 640 individuals in a general population survey in China. From the 4 items, 11 compound items were constructed, and the 'worse level counts' rule was used to calculate a compound item score. Psychometric performance of the cognition bolt-ons was assessed in terms of informativity, convergent validity, explanatory power, and discriminatory power.
The tested four cognition bolt-on items improved the informativity, convergent validity, explanatory power, and discriminatory power of EQ-5D-5L, with calculation and learning yielding better psychometric performance. The compound bolt-on items that coverd a range of cognitive functions demonstrated superior psychometric performance compared to single-aspect bolt-on items, with those items covering calculation and learning resulting in better psychometric performance.
This study confirmed the validity of the tested cognition bolt-ons in a general Chinese population. It supported the use of a compound bolt-on item covering a range of cognitive functions such as the ability to calculate and learn.
本研究旨在评估四个候选认知附加项目及其组合对EQ-5D-5L的心理测量特性。
四个认知项目（注意力、记忆力、计算能力和学习能力）被开发为单独的问卷项目，并在中国的一项普通人群调查中与标准的EQ-5D-5L一起施用于640名个体。从这4个项目中构建了11个复合项目，并使用“较差水平计数”规则计算复合项目得分。从信息性、收敛效度、解释力和区分力方面评估认知附加项目的心理测量性能。
测试的四个认知附加项目提高了EQ-5D-5L的信息性、收敛效度、解释力和区分力，计算能力和学习能力的心理测量性能更好。涵盖一系列认知功能的复合附加项目比单一方面的附加项目表现出更好的心理测量性能，其中涵盖计算能力和学习能力的项目心理测量性能更佳。
本研究证实了测试的认知附加项目在中国普通人群中的有效性。它支持使用涵盖一系列认知功能（如计算和学习能力）的复合附加项目。
