Department of General Surgery, Yuksek Ihtisas Education and Training Hospital, Mimarsinan Mah. Emniyet Cad. Yıldırım, Bursa, 16310, Turkey.
Private Hayat Hospital, Obesity and Metabolic Surgery Center, Bursa, Turkey.
Obes Surg. 2024 Oct;34(10):3748-3754. doi: 10.1007/s11695-024-07472-2. Epub 2024 Aug 20.
The rapid increase in obesity and related problems has heightened the importance of obesity and metabolic surgery, resulting in a continuing search for the ideal surgical method. This study aimed to compare the effectiveness of Roux-en-Y gastric bypass (RYGB), which is the gold standard method, and the relatively newer method of single anastomosis sleeve ileal (SASI) bypass.
The medical records of patients who underwent RYGB and SASI bypass were reviewed and compared regarding excess weight loss (EWL) and HgA1c, fasting glucose, serum iron, ferritin, hemoglobin (Hgb), and vitamin B12 levels.
The body mass index was significantly lower (p = 0.003), and the %EWL was significantly higher (p = 0.023) at 6 months postoperative in patients who underwent SASI bypass. Both groups had similar results at the other follow-up visits. The mean HgA1c levels at the 6- and 12-month follow-up visits were significantly lower in SASI patients (p = 0.037 and p = 0.012, respectively). At the 24-month follow-up, no difference was detected in HgA1c levels between the groups (p = 0.476). In patients who underwent RYGB, ferritin (p < 0.001), plasma iron (p = 0.001), and Hgb levels (p = 0.001) were significantly lower at 12, 24, and 12 months postoperatively, respectively.
SASI bypass is effective and comparable to RYGB in terms of EWL and metabolic control and has the advantage of not producing excluded segments and reducing nutritional deficiencies.
肥胖及其相关问题的迅速增加，提高了肥胖和代谢手术的重要性，促使人们不断寻找理想的手术方法。本研究旨在比较 Roux-en-Y 胃旁路术（RYGB）作为金标准方法和相对较新的单吻合口袖状空肠旁路术（SASI）的效果。
回顾性分析接受 RYGB 和 SASI 旁路手术的患者的病历，比较两组患者的超重减轻量（EWL）和糖化血红蛋白（HgA1c）、空腹血糖、血清铁、铁蛋白、血红蛋白（Hgb）和维生素 B12 水平。
SASI 旁路组患者术后 6 个月体重指数显著降低（p=0.003），EWL 显著升高（p=0.023）。两组在其他随访时的结果相似。SASI 组患者在 6 个月和 12 个月的随访中平均 HgA1c 水平显著降低（p=0.037 和 p=0.012）。在 24 个月的随访中，两组的 HgA1c 水平无差异（p=0.476）。RYGB 组患者的铁蛋白（p<0.001）、血浆铁（p=0.001）和 Hgb 水平（p=0.001）在术后 12、24 和 12 个月时均显著降低。
SASI 旁路在超重减轻和代谢控制方面与 RYGB 一样有效，且具有不产生被排除的肠段和减少营养缺乏的优势。
