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一篇关于癌症能量重编程对耐药性和免疫反应的小型综述

A mini-review-cancer energy reprogramming on drug resistance and immune response.

作者信息

Liu Chengxiang, Yang Liuxin, Gao Tingting, Yuan Xingxing, Bajinka Ousman, Wang Kuanyu

机构信息

School of Graduate Studies, Heilongjiang University of Chinese Medicine, Harbin 150040, China; Department of Dermatology, Heilongjiang Academy of Traditional Chinese Medicine, Harbin 150006, China.

School of Graduate Studies, Heilongjiang University of Chinese Medicine, Harbin 150040, China.

出版信息

Transl Oncol. 2024 Nov;49:102099. doi: 10.1016/j.tranon.2024.102099. Epub 2024 Aug 19.

DOI:10.1016/j.tranon.2024.102099
PMID:39163759
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11380382/
Abstract

With the growing interest to harness cancer metabolism and energy reprogramming, this mini review aimed to explain the metabolic programming revealing the mechanisms regarding the treatment resistance. This mini review summarized the prominent cancer metabolic reprogramming on macromolecules. In addition, metabolic reprogramming explaining immune response and treatment resistance as well as energy reprogramming mechanisms are briefly discussed. Finally, some prospects in MR for reversing cancer drug resistance are highlighted.

摘要

随着利用癌症代谢和能量重编程的兴趣日益增长，本综述旨在解释揭示治疗耐药机制的代谢编程。本综述总结了大分子上突出的癌症代谢重编程。此外，还简要讨论了解释免疫反应和治疗耐药性的代谢重编程以及能量重编程机制。最后，强调了磁共振成像在逆转癌症耐药性方面的一些前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbc7/11380382/3daaeffb612b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbc7/11380382/d4d27d4f33d7/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbc7/11380382/16ec833b3376/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbc7/11380382/3daaeffb612b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbc7/11380382/d4d27d4f33d7/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbc7/11380382/16ec833b3376/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbc7/11380382/3daaeffb612b/gr2.jpg

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Cancer Commun (Lond). 2024 Mar;44(3):408-432. doi: 10.1002/cac2.12525. Epub 2024 Feb 26.
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Front Pharmacol. 2024 Oct 17;15:1450441. doi: 10.3389/fphar.2024.1450441. eCollection 2024.
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J Hematol Oncol. 2023 Sep 12;16(1):103. doi: 10.1186/s13045-023-01498-2.
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