Lam Lisetta, Ivanovski Saso, Lee Ryan S B
School of Dentistry, The University of Queensland, Brisbane, Queensland, Australia.
Centre for Orofacial Regeneration, Rehabilitation and Reconstruction (COR3), School of Dentistry, The University of Queensland, Brisbane, Queensland, Australia.
Clin Oral Implants Res. 2024 Dec;35(12):1568-1584. doi: 10.1111/clr.14344. Epub 2024 Aug 21.
To investigate the effects of alveolar ridge preservation (ARP) on ridge height, sinus pneumatization and the potential need for lateral sinus augmentation following extraction in the posterior maxilla.
This randomized controlled pilot study included 28 patients requiring extraction in the posterior maxilla with bone height between 6 and 8 mm. The sites were randomly allocated to either unassisted socket healing (Control), ARP with deproteinized bovine bone mineral (DBBM) (Test 1), or collagen-stabilized DBBM (Test 2) groups. Pre- and post-operative CTs at 4 months were taken to determine changes in ridge heights, sinus volume, and the need for sinus floor elevation (SFE) procedures for cases where the residual mid-ridge height was < 5 mm. Site-level analyses for changes in vertical ridge dimensions and sinus volume pre- and post-extraction/ARP were conducted using paired t-tests. Differences in mean changes in vertical ridge dimensions and sinus volume between the groups were determined using one-way ANOVA.
Significantly greater mean mid-ridge height reduction occurred in the control group (-2.7 ± 0.9 mm) compared to Test 1 (0.9 ± 3.7 mm) and Test 2 (1.0 ± 2.8 mm) groups (p < .05). No significant changes in mean mid-ridge height were found in either test groups. Volumetric analysis showed a significantly greater increase in sinus volume in the control group (0.7 ± 0.7 cm) compared to Test 1 (n = 3, -0.7 ± 0.8 cm) group (p = .03). 89% of patients in the control group would require lateral window SFE compared to Test 1 (42.8%) and Test 2 (40%) groups.
ARP was effective in attenuating height changes in the middle of the ridge and may reduce sinus pneumatization following extraction in the posterior maxilla. This could potentially decrease the need for more invasive sinus augmentation procedures.
研究上颌后牙区拔牙后牙槽嵴保存(ARP)对牙槽嵴高度、上颌窦气化以及后期上颌窦外侧壁增高术潜在需求的影响。
本随机对照试验纳入了28例上颌后牙区需要拔牙且牙槽骨高度在6至8毫米之间的患者。这些位点被随机分配至无辅助拔牙创愈合组(对照组)、使用脱蛋白牛骨矿物质(DBBM)的牙槽嵴保存组(试验1组)或胶原稳定化DBBM组(试验2组)。在4个月时进行术前和术后CT扫描,以确定牙槽嵴高度、上颌窦容积的变化,以及对于剩余牙槽嵴顶高度<5毫米的病例是否需要进行上颌窦底提升(SFE)手术。使用配对t检验对拔牙/牙槽嵴保存前后垂直牙槽嵴尺寸和上颌窦容积的变化进行位点水平分析。使用单因素方差分析确定各组之间垂直牙槽嵴尺寸和上颌窦容积平均变化的差异。
与试验1组(0.9±3.7毫米)和试验2组(1.0±2.8毫米)相比,对照组(-2.7±0.9毫米)的平均牙槽嵴顶高度降低更为显著(p<.05)。在两个试验组中均未发现平均牙槽嵴顶高度有显著变化。容积分析显示,与试验1组(n = 3,-0.7±0.8立方厘米)相比,对照组(0.7±0.7立方厘米)的上颌窦容积增加更为显著(p = .03)。与试验1组(42.8%)和试验2组(40%)相比,对照组中89%的患者需要进行外侧开窗式上颌窦底提升术。
牙槽嵴保存术能有效减轻牙槽嵴中部的高度变化,并可能减少上颌后牙区拔牙后的上颌窦气化。这可能会减少对侵入性更强的上颌窦增高手术的需求。