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开放式愈合拔牙位点的牙槽嵴保存:一项随机对照临床试验。

Ridge preservation in molar extraction sites with an open-healing approach: A randomized controlled clinical trial.

机构信息

Department of Periodontology, School of Dentistry, Periodontal-Implant Clinical Research Institute, Kyung Hee University, Seoul, South Korea.

Department of Periodontology, Dankook University College of Dentistry, Cheonan-si, South Korea.

出版信息

J Clin Periodontol. 2019 Nov;46(11):1144-1154. doi: 10.1111/jcpe.13184. Epub 2019 Sep 9.

DOI:10.1111/jcpe.13184
PMID:31444908
Abstract

AIM

To determine the effect of alveolar ridge preservation (ARP) in molar sites without primary flap closure.

MATERIALS AND METHODS

Three groups were established: extraction sockets grafted with deproteinized bovine bone mineral containing 10% collagen (DBBM-C) and covered by a native bilayer collagen membrane (NBCM) (test group 1), sockets grafted with DBBM-C only (test group 2), and sockets that healed naturally (control group). Primary flap closure was not attempted. Conebeam computed tomography scans were obtained immediately and then 4 months after ARP. A biopsy was performed. The change of the marginal bone level was measured.

RESULTS

There was significantly less horizontal resorption in test group 1 than in the control group at levels 1 mm (-1.02 ± 0.88 [mean ± SD] vs. -4.44 ± 3.71 mm) and 3 mm (-0.31 ± 1.51 vs. -2.27 ± 1.15 mm) below the crest, and significantly less vertical reduction in the midcrestal area in test group 1 than in test group 2 (-0.25 ± 0.95 vs. -1.15 ± 1.63 mm) (p < .05). There were no significant differences between test groups in clinical and histomorphometric measurements. All groups exhibited stable marginal bone levels after 1 year of loading.

CONCLUSION

Alveolar ridge preservation without primary flap closure in molar areas was effective in minimizing ridge resorption and facilitated implant treatment.

摘要

目的

确定不进行原发性皮瓣关闭的磨牙区牙槽嵴保存(ARP)的效果。

材料和方法

建立了三组:用含 10%胶原的脱蛋白牛骨矿物质(DBBM-C)和天然双层胶原膜(NBCM)覆盖的拔牙窝(实验组 1)、仅用 DBBM-C 移植的拔牙窝(实验组 2)和自然愈合的拔牙窝(对照组)。不尝试进行原发性皮瓣关闭。ARP 后即刻和 4 个月时进行锥形束 CT 扫描。进行活检。测量边缘骨水平的变化。

结果

在 1mm (-1.02 ± 0.88 [平均值 ± 标准差] 与 -4.44 ± 3.71mm)和 3mm (-0.31 ± 1.51 与 -2.27 ± 1.15mm)牙槽嵴以下水平,实验组 1 的水平吸收明显少于对照组,在中嵴区域的垂直减少量也明显少于实验组 2(-0.25 ± 0.95 与 -1.15 ± 1.63mm)(p < 0.05)。在临床和组织形态计量学测量方面,实验组之间没有差异。所有组在 1 年负荷后均显示稳定的边缘骨水平。

结论

磨牙区不进行原发性皮瓣关闭的牙槽嵴保存可有效减少牙槽嵴吸收,并有利于种植治疗。

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