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经皮注射博来霉素治疗腰椎滑膜囊肿:一例报告。

Percutaneous treatment of lumbar synovial cysts with bleomycin: A case report.

作者信息

Newman Sharle, Tejada Juan G, Khan Majid, Martinez Mesha L

机构信息

Department of Family Medicine, Wright State Boonshoft School of Medicine, Dayton, OH, USA.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Eskenazi Hospital, Indianapolis, IN, USA.

出版信息

Interv Neuroradiol. 2024 Aug 21:15910199241273973. doi: 10.1177/15910199241273973.

DOI:10.1177/15910199241273973
PMID:39165193
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11569716/
Abstract

Lumbar synovial cysts (LSC) that protrude into the spinal canal can cause lower back pain, neurogenic claudication, and radiculopathy. Often diagnosed in the elderly population (typically ∼60 years of age) with a slight preponderance for females, their underlying etiology is thought to be due to degeneration of the adjacent facet joint, with the most common location at the level of L4-L5. Treatment of LSC can be conservative (with NSAIDs and physical therapy), percutaneous (with rupture), or surgically (with decompression with or without fusion). Percutaneous treatment of LSC involves rupturing the cyst by injecting it with steroids and local anesthetics. Although this option is less invasive than surgery, multiple studies have documented recurrence with this method and patients eventually undergoing surgical intervention. In this report, we document a case where a patient who presented with a symptomatic LSC underwent successful percutaneous treatment with bleomycin.

摘要

突入椎管的腰椎滑膜囊肿(LSC)可导致下背部疼痛、神经源性间歇性跛行和神经根病。LSC常诊断于老年人群(通常约60岁),女性略占多数,其潜在病因被认为是相邻小关节退变,最常见部位在L4 - L5水平。LSC的治疗方法可以是保守治疗(使用非甾体抗炎药和物理治疗)、经皮治疗(囊肿破裂)或手术治疗(减压,可伴有或不伴有融合)。LSC的经皮治疗包括通过向囊肿内注射类固醇和局部麻醉剂使其破裂。尽管此方法比手术侵入性小,但多项研究记录了该方法的复发情况,患者最终仍需接受手术干预。在本报告中,我们记录了一例有症状的LSC患者接受博来霉素经皮治疗成功的病例。

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本文引用的文献

1
Benefit of Intracystic Bleomycin for Symptomatic Recurrent Rathke Cleft Cyst.囊内注射平阳霉素治疗有症状的复发性 Rathke 裂囊肿的获益。
Oper Neurosurg (Hagerstown). 2019 Sep 1;17(3):268-272. doi: 10.1093/ons/opy361.
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Long-term outcomes of percutaneous lumbar facet synovial cyst rupture.经皮腰椎小关节滑膜囊肿破裂的长期预后
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Intralesional Bleomycin Injections for Vascular Malformations: A Systematic Review and Meta-Analysis.注射博来霉素治疗血管畸形:一项系统评价和荟萃分析
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Percutaneous resolution of lumbar facet joint cysts as an alternative treatment to surgery: a meta-analysis.经皮腰椎小关节囊肿消融术作为手术的替代治疗方法:一项荟萃分析
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Improved outcomes with direct percutaneous CT guided lumbar synovial cyst treatment: advanced approaches and techniques.直接经皮CT引导下腰椎滑膜囊肿治疗的改善结果:先进方法与技术
J Neurointerv Surg. 2014 Dec;6(10):790-4. doi: 10.1136/neurintsurg-2013-010891. Epub 2013 Nov 26.
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