Mahmoud Hivi, Saifdeen Payman M, Al-Timimi Dhia, Saeed Sedghi A
Medical Chemistry, College of Medicine, University of Duhok, Duhok, IRQ.
Dermatology, Azadi General Teaching Hospital, Duhok, IRQ.
Cureus. 2024 Aug 20;16(8):e67264. doi: 10.7759/cureus.67264. eCollection 2024 Aug.
Zinc is an essential element for hair growth and may act as a strong inhibitor in accelerating follicle regression, besides being an accelerator for the recovery of the hair follicle. This study investigated the status of zinc in Kurdish adults with hair loss and its relation with each of the four types of hair loss.
We investigated the zinc status of a sample of Kurdish adults with hair loss who attended the Dermatology Outpatient Clinics at Azadi Teaching Hospital in Duhok, Kurdistan Region, Iraq. We included a total of 200 subjects in this study, of which 125 had hair loss with a diagnosis of alopecia areata, female pattern hair loss, male pattern hair loss, and telogen effluvium, and 75 were sex- and age-matched apparently healthy subjects without hair fall as a control group. Serum samples were used to measure zinc by colorimetric technique.
In participants with hair loss, we found significantly lower serum zinc levels (p=0.002) compared with the control group. The telogen effluvium group had the lowest mean serum zinc level (p=0.006) and higher odds ratio compared with other hair loss groups (4.61). Overall, severe zinc deficiency was found in 12 (9.6%) subjects with hair loss, whereas none of the controls had severe zinc deficiency. Mild-to-moderate zinc deficiency was observed in 43 (34.4%) subjects with hair loss compared to one (1.3%) in the control group. Conclusions: Our results showed that lower zinc status is linked to hair loss, especially alopecia areata and telogen effluvium in the Kurdish population.
锌是头发生长的必需元素，除了能促进毛囊恢复外，还可能是加速毛囊退化的强效抑制剂。本研究调查了库尔德族脱发成年人的锌状态及其与四种脱发类型中每种类型的关系。
我们调查了伊拉克库尔德地区杜胡克阿扎迪教学医院皮肤科门诊的库尔德族脱发成年人样本的锌状态。本研究共纳入200名受试者，其中125名患有斑秃、女性型脱发、男性型脱发和休止期脱发的脱发患者，75名年龄和性别匹配的明显健康且无脱发的受试者作为对照组。采用比色法测定血清样本中的锌。
与对照组相比，脱发参与者的血清锌水平显著降低（p=0.002）。休止期脱发组的平均血清锌水平最低（p=0.006），与其他脱发组相比，优势比更高（4.61）。总体而言，12名（9.6%）脱发受试者存在严重锌缺乏，而对照组中无一例严重锌缺乏。43名（34.4%）脱发受试者观察到轻度至中度锌缺乏，而对照组中只有1名（1.3%）。结论：我们的结果表明，锌状态较低与脱发有关，尤其是库尔德人群中的斑秃和休止期脱发。
