Rouzbahani Maedeh, Husnain Ali, Badar Wali, Ahmed Osman
Advanced Diagnostic and Interventional Radiologic Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Department of Radiology, King Edward Medical University, Lahore, Pakistan.
Semin Intervent Radiol. 2024 Aug 19;41(3):246-251. doi: 10.1055/s-0044-1788029. eCollection 2024 Jun.
Osteoarthritis (OA) of the knee is a degenerative condition impacting numerous individuals globally. Genicular artery embolization (GAE) has emerged as an effective minimally invasive therapy for managing medically refractory OA-related pain in patients who are not eligible for surgery. This intervention works by disrupting the inflammatory and neoangiogenic pathways that contribute to pain. The efficacy of GAE has been demonstrated in various clinical trials, yielding promising results. This review aims to explore recent advancements in the embolic materials used during GAE, examining their properties and potential benefits. Additionally, it will describe the use of pre-, intra-, and postprocedural imaging-particularly magnetic resonance imaging and other modalities-to optimize GAE outcomes.
膝关节骨关节炎(OA)是一种退行性疾病,影响着全球众多人群。膝下动脉栓塞术(GAE)已成为一种有效的微创治疗方法,用于治疗那些不适合手术的、药物治疗难治性OA相关疼痛的患者。这种干预措施通过破坏导致疼痛的炎症和新生血管生成途径来发挥作用。GAE的疗效已在各种临床试验中得到证实,取得了有前景的结果。本综述旨在探讨GAE期间使用的栓塞材料的最新进展,研究其特性和潜在益处。此外,还将描述术前、术中和术后成像(特别是磁共振成像和其他模式)的使用,以优化GAE的治疗效果。