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两种源自 l(+)-酒石酸低分子量凝胶剂的新型超分子金属凝胶的高效抗菌应用。

Efficient antimicrobial applications of two novel supramolecular metallogels derived from a l(+)-tartaric acid low molecular weight gelator.

作者信息

Dhibaris Subhendu, Pal Suchetana, Some Sangita, Karmakar Kripasindhu, Saha Ratnakar, Bhattacharjee Subham, Roy Arpita, Ray Soumya Jyoti, Ajiboye Timothy O, Dam Somasri, Saha Bidyut

机构信息

Colloid Chemistry Laboratory, Department of Chemistry, The University of Burdwan Golapbag Burdwan 713104 West Bengal India

Department of Microbiology, The University of Burdwan Burdwan 713104 West Bengal India

出版信息

RSC Adv. 2024 Aug 20;14(36):26354-26361. doi: 10.1039/d4ra03451a. eCollection 2024 Aug 16.

Abstract

Novel metallogels were synthesized using l(+)-tartaric acid as a gelator, along with cadmium(ii)-acetate and mercury(ii)-acetate in ,-dimethyl formamide at room temperature. Rheological analyses confirmed the mechanical stability of Cd(ii)- and Hg(ii)-metallogels under varying conditions. Characterization through EDX mapping and FESEM imaging provided insights into their chemical constituents and microstructural features. FT-IR spectroscopy elucidated the metallogel formation mechanism. Antimicrobial assays revealed significant activity against various bacteria, including Gram-positive and Gram-negative strains. This study presents a comprehensive exploration of Cd(ii) and Hg(ii)-based l(+)-tartaric acid-mediated metallogels, highlighting their potential in combating bacterial infections. These findings suggest promising applications in both industrial and biomedical fields, offering avenues for the development of advanced materials.

摘要

在室温下,以L(+)-酒石酸为胶凝剂,与醋酸镉(ii)和醋酸汞(ii)一起在N,N-二甲基甲酰胺中合成了新型金属凝胶。流变学分析证实了镉(ii)和汞(ii)金属凝胶在不同条件下的机械稳定性。通过能谱分析(EDX)和场发射扫描电子显微镜(FESEM)成像进行表征,深入了解了它们的化学成分和微观结构特征。傅里叶变换红外光谱(FT-IR)阐明了金属凝胶的形成机制。抗菌试验表明,它们对包括革兰氏阳性菌和革兰氏阴性菌在内的各种细菌具有显著活性。本研究全面探索了基于镉(ii)和汞(ii)的L(+)-酒石酸介导的金属凝胶,突出了它们在对抗细菌感染方面的潜力。这些发现表明,它们在工业和生物医学领域都有广阔的应用前景,为先进材料的开发提供了途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b80b/11334155/0b18ec34c592/d4ra03451a-f1.jpg

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