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单侧脉络膜转移作为小细胞肺癌的一种不寻常表现

Unilateral choroidal metastases as an unusual presentation of small cell lung cancer.

作者信息

Anwar Junaid, Amin Toka, Sarfraz Zouina, Khalid Musfira, Khan Muhammad Shariq, Abdelhakeem Ahmed

机构信息

Department of Medicine, Baptist Hospitals of Southeast Texas, Beaumont, Texas, USA.

Department of Medicine, Icahn School of Medicine at Mount Sinai/Queens Hospital, New York, New York, USA.

出版信息

Proc (Bayl Univ Med Cent). 2024 Jun 3;37(5):870-873. doi: 10.1080/08998280.2024.2356517. eCollection 2024.

Abstract

The choroid, rich in vasculature, is a common site for ocular metastases, predominantly from breast and lung cancer. Unlike breast cancer, which may cause bilateral involvement, lung cancer typically leads to unilateral lesions. Adenocarcinoma is the primary lung cancer subtype associated with choroidal metastasis, while small cell lung cancer (SCLC) infrequently involves the choroid. In our case, a 69-year-old man with hypertension, hyperlipidemia, and chronic obstructive pulmonary disease presented with right eye visual disturbances and was diagnosed with choroidal metastasis. Subsequent imaging revealed lung cancer with widespread metastasis. Despite treatment postponement due to deteriorating health, the patient's condition worsened, leading to palliative care discharge. Despite its rarity, choroidal involvement in SCLC warrants further investigation to enhance diagnostic and therapeutic strategies. This case highlights the importance of meticulous evaluation and interdisciplinary care to optimize outcomes in patients with SCLC and choroidal metastasis.

摘要

脉络膜血管丰富,是眼部转移瘤的常见部位,主要源自乳腺癌和肺癌。与可能导致双侧受累的乳腺癌不同,肺癌通常导致单侧病变。腺癌是与脉络膜转移相关的主要肺癌亚型,而小细胞肺癌(SCLC)很少累及脉络膜。在我们的病例中,一名患有高血压、高脂血症和慢性阻塞性肺疾病的69岁男性因右眼视力障碍就诊,被诊断为脉络膜转移瘤。随后的影像学检查显示为伴有广泛转移的肺癌。尽管由于健康状况恶化而推迟了治疗,但患者的病情仍恶化,最终出院接受姑息治疗。尽管SCLC累及脉络膜罕见,但仍需进一步研究以改进诊断和治疗策略。该病例强调了细致评估和多学科护理对于优化SCLC合并脉络膜转移患者治疗效果的重要性。

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Unilateral choroidal metastases as an unusual presentation of small cell lung cancer.单侧脉络膜转移作为小细胞肺癌的一种不寻常表现
Proc (Bayl Univ Med Cent). 2024 Jun 3;37(5):870-873. doi: 10.1080/08998280.2024.2356517. eCollection 2024.
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A Comprehensive Understanding of Choroidal Metastasis from Lung Cancer.对肺癌脉络膜转移的全面认识。
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Small-cell lung cancer.小细胞肺癌。
Nat Rev Dis Primers. 2021 Jan 14;7(1):3. doi: 10.1038/s41572-020-00235-0.
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Metastatic sites and survival in lung cancer.肺癌的转移部位与生存情况
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