Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.
Hospital San Bartolomé, Lima, Perú.
Rev Peru Med Exp Salud Publica. 2024 Aug 19;41(2):178-184. doi: 10.17843/rpmesp.2024.412.13293.
Motivation for the study. There is a gap in knowledge about vertical transmission of SARS- CoV-2 and its implications for maternal and neonatal health, despite evidence of multisystem involvement in pregnant women with COVID-19. Main findings. The study results suggest low incidence of vertical transmission during pregnancy, with only one PCR-positive case in the placenta and one asymptomatic neonate. Implications. Our results can inform strategies for prevention and management of COVID-19 in pregnant women, as well as guide the development of health policies aimed at protecting maternal and neonatal health during the pandemic. The aim of this study was to analyze the vertical transmission of SARS-CoV-2 in pregnant women with COVID-19 in the Gynecology and Obstetrics Department of the Edgardo Rebagliati Martins National Hospital (HNERM). Twelve pregnant women who met the inclusion criteria were included. Real-time PCR (RT-PCR) tests for SARS-CoV-2 were performed when each woman was admitted to the hospital, placenta samples were collected for pathological evaluation as well. The results showed that vertical transmission of the virus was rare, with an overall low positivity rate in newborns. Although the study has limitations, such as the small number of cases and the lack of electron microscope analysis, it is the first attempt to evaluate vertical transmission in Peru. It is concluded that more research is needed to better understand the relationship between COVID-19 infection and complications during pregnancy.
研究动机。尽管有证据表明 COVID-19 孕妇存在多系统受累，但对于 SARS-CoV-2 的垂直传播及其对母婴健康的影响，知识仍存在空白。主要发现。研究结果表明，妊娠期间垂直传播的发生率较低，胎盘中仅发现一例 PCR 阳性病例，一例无症状新生儿。意义。我们的研究结果可以为 COVID-19 孕妇的预防和管理策略提供信息，并指导旨在保护大流行期间母婴健康的卫生政策的制定。本研究旨在分析 COVID-19 孕妇在埃德华多·雷巴利亚特·马丁内斯国家医院（HNERM）妇产科的垂直传播情况。纳入了符合纳入标准的 12 名孕妇。每位女性入院时均进行了实时 PCR（RT-PCR）检测 SARS-CoV-2，胎盘样本也进行了病理评估。结果表明，病毒的垂直传播罕见，新生儿总体阳性率较低。尽管该研究存在一些局限性，例如病例数量少和缺乏电子显微镜分析，但它是秘鲁首次尝试评估垂直传播。结论是，需要进一步研究以更好地了解 COVID-19 感染与妊娠并发症之间的关系。
