Okamoto Tatsuya, Ogawa Eri, Okajima Hideaki, Masano Yuki, Okumura Shinya, Yamamoto Miki, Uebayashi Elena Yukie, Suga Takenori, Hiejima Eitaro, Yamamoto Shuji, Haga Hironori, Ito Takashi, Hatano Etsuro
Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.
Department of Pediatric Surgery, Kyoto University Hospital, Kyoto, 606-8507, Japan.
Surg Today. 2025 May;55(5):716-722. doi: 10.1007/s00595-024-02923-w. Epub 2024 Aug 21.
Children with intestinal failure suffer liver damage associated with parenteral nutrition: a condition known as intestinal failure-associated liver disease (IFALD), which requires transplantation of both liver and intestine. In many countries, simultaneous transplantation of these two organs is performed using grafts from a deceased donor, but there have been no such cases in Japan, and the details of the procedure are not clear. Recently, we performed simultaneous split liver and intestinal transplantation in two premature infants with IFALD, using organs from identical deceased donors and achieved good results. These are the first two cases of this procedure being performed in Japan. We report these cases and discuss the important aspects of the surgical and perioperative management.
一种称为肠衰竭相关肝病（IFALD）的病症，这需要进行肝脏和肠道移植。在许多国家，使用已故供体的移植物进行这两个器官的同时移植，但在日本尚无此类病例，且该手术的细节尚不清楚。最近，我们对两名患有IFALD的早产儿进行了肝脏和肠道同时劈离移植，使用来自同一位已故供体的器官，并取得了良好的效果。这是日本首次进行此类手术的两例病例。我们报告这些病例并讨论手术及围手术期管理的重要方面。
