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芬太尼检测条用于减少伤害的质量保证的大量检测方案。

A lot testing protocol for quality assurance of fentanyl test strips for harm reduction applications.

机构信息

Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 46556, USA.

出版信息

Harm Reduct J. 2024 Aug 21;21(1):152. doi: 10.1186/s12954-024-01058-y.

DOI:10.1186/s12954-024-01058-y
PMID:39169393
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11337861/
Abstract

Fentanyl test strips (FTS) are lateral flow immunoassays that were originally designed and validated for detecting low concentrations of fentanyl in urine. Some FTS are now being marketed for the harm reduction purpose of testing street drugs for the presence of fentanyl. This manuscript provides a simple protocol to assess whether different brands and lots of fentanyl test strips perform adequately for use in drug checking. The results gathered from this protocol will document problems with particular lots or brands of FTS, help buyers choose from among the array of products, provide feedback to manufacturers to improve their products, and serve as an early warning system for ineffective products.

摘要

芬太尼检测试纸(FTS)是侧向流免疫分析,最初设计并验证用于检测尿液中低浓度的芬太尼。现在,一些芬太尼检测试纸正被推向市场,用于减少伤害,检测街头毒品中是否存在芬太尼。本文提供了一个简单的方案,用于评估不同品牌和批次的芬太尼检测试纸是否能充分用于毒品检测。从该方案中收集的结果将记录特定批次或品牌的 FTS 存在的问题,帮助购买者在众多产品中进行选择,为制造商提供改进产品的反馈,并作为无效产品的早期预警系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/613e/11337861/0154745e0754/12954_2024_1058_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/613e/11337861/0154745e0754/12954_2024_1058_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/613e/11337861/0154745e0754/12954_2024_1058_Fig1_HTML.jpg

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本文引用的文献

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2
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Harm Reduct J. 2024 Jan 18;21(1):14. doi: 10.1186/s12954-023-00921-8.
3
"If I had them, I would use them every time": Perspectives on fentanyl test strip use from people who use drugs.
如果我有这些测试条,我每次都会用它们": 吸毒者对芬太尼测试条使用的看法。
J Subst Abuse Treat. 2022 Sep;140:108790. doi: 10.1016/j.jsat.2022.108790. Epub 2022 May 5.
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Clinical Pharmacology, Toxicity, and Abuse Potential of Opioids.阿片类药物的临床药理学、毒性和滥用潜力。
J Clin Pharmacol. 2021 Aug;61 Suppl 2:S70-S88. doi: 10.1002/jcph.1923.
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