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伊利扎洛夫外固定器与Orthofix LRS在股骨骨髓炎治疗中的比较:倾向评分匹配分析

Ilizarov External Fixator Versus Orthofix LRS in Management of Femoral Osteomyelitis: A Propensity Score Matched Analysis.

作者信息

Saleh Ayman K, Yusof Nazri Mohd, Attallah Abdehamid A, Elshal Ehab Abdelftah, Khames Amr Abdelhalem Amr, Ibrahim Mohamed Nagah Ahmed, Mahmoud Mohamed Mosa Mohamed, Abdeltawab Gaber Eid, Abuomira Ibrahim Elsayed Abdellatif A

机构信息

Department of Surgery, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.

Department of Orthopedic Surgery, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.

出版信息

Indian J Orthop. 2024 Jul 7;58(9):1272-1277. doi: 10.1007/s43465-024-01208-1. eCollection 2024 Sep.

Abstract

PURPOSE

Treatment of osteomyelitis (OM) is challenging. Ilizarov bone transport is a commonly used technique for management of OM. The recently introduced limb reconstruction system (LRS) has been effectively used for management of OM. It was suggested to be easier in use and less invasive. The present retrospective study aimed to compare LRS and Ilizarov bone transport in management of femoral OM using a propensity score matched analysis.

METHODS

The present retrospective study included 80 consecutive patients with femoral OM. The studied patients were managed either using Ilizarov external fixator ( = 40) or Orthofix LRS ( = 40). The clinical outcome measurements included union time, limb length discrepancy, additional operative procedures, refracture and infection.

RESULTS

Patients in the LRS group were exposed to significantly higher frequency of bone transport (30.0 versus 15.0%) and lower frequency of acute compression and lengthening (10.0 versus 32.5%). Patients in Ilizarov group had significantly higher frequency of tobramycin pellets as compared to their counterparts. The studied groups were comparable regarding the operative complications including pin-tract infection, non-union at docking site and refracture. Patients in the Ilizarov had significantly shorter time to union (8.2 ± 3.2 versus 11.0 ± 5.6 months,  = 0.012). No statistically significant differences were found between the studied groups regarding the quality-of-life domains.

CONCLUSIONS

Use of Ilizarov external fixator and Orthofix LRS devices proved to be effective and reliable. Their influences on patients' quality appear to be comparable.

摘要

目的

骨髓炎(OM)的治疗具有挑战性。伊里扎洛夫骨搬运是治疗OM常用的技术。最近推出的肢体重建系统(LRS)已有效地用于OM的治疗。有人认为它使用起来更容易且侵入性更小。本回顾性研究旨在通过倾向评分匹配分析比较LRS和伊里扎洛夫骨搬运在股骨OM治疗中的效果。

方法

本回顾性研究纳入了80例连续的股骨OM患者。所研究的患者分别采用伊里扎洛夫外固定架(n = 40)或奥托菲克斯LRS(n = 40)进行治疗。临床结局指标包括愈合时间、肢体长度差异、额外的手术操作、再骨折和感染。

结果

LRS组患者进行骨搬运的频率显著更高(30.0%对15.0%),急性加压和延长的频率更低(10.0%对32.5%)。与LRS组患者相比,伊里扎洛夫组患者使用妥布霉素颗粒的频率显著更高。在包括针道感染、对接部位不愈合和再骨折在内的手术并发症方面,所研究的两组具有可比性。伊里扎洛夫组患者的愈合时间显著更短(8.2±3.2个月对11.0±5.6个月,P = 0.012)。在所研究的两组之间,在生活质量方面未发现统计学上的显著差异。

结论

使用伊里扎洛夫外固定架和奥托菲克斯LRS装置被证明是有效且可靠的。它们对患者生活质量的影响似乎相当。

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