增强T细胞作为预防H3N2流感通用措施的应用：机制与意义 - Suppr

Suppr

超能文献

Enhancing the use of T cells as a universal preventive measure against H3N2 influenza: Mechanism and implications.

作者信息

Bhatt Jugal Hiren, Kagathara Nency, Mehta Kahan, Joshi Maurya, Omar Mohamed A

机构信息

Department of Internal Medicine GMERS Medical College Gotri Vadodara India.

Department of Medicine Zydus Medical College Dahod India.

出版信息

Health Sci Rep. 2024 Aug 20;7(8):e70004. doi: 10.1002/hsr2.70004. eCollection 2024 Aug.

DOI:10.1002/hsr2.70004

PMID:39170886

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11335571/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c96e/11335571/c32ba3d940eb/HSR2-7-e70004-g001.jpg

相似文献

Enhancing the use of T cells as a universal preventive measure against H3N2 influenza: Mechanism and implications.增强T细胞作为预防H3N2流感通用措施的应用：机制与意义

Health Sci Rep. 2024 Aug 20;7(8):e70004. doi: 10.1002/hsr2.70004. eCollection 2024 Aug.

Effectiveness of influenza vaccine against influenza A in Europe in seasons of different A(H1N1)pdm09 and the same A(H3N2) vaccine components (2016-17 and 2017-18).在欧洲不同甲型H1N1pdm09流行季且甲型H3N2疫苗成分相同的季节（2016 - 17年和2017 - 18年），流感疫苗对甲型流感的有效性。

Vaccine X. 2019 Sep 17;3:100042. doi: 10.1016/j.jvacx.2019.100042. eCollection 2019 Dec 10.

An epitope-optimized human H3N2 influenza vaccine induces broadly protective immunity in mice and ferrets.一种表位优化的人H3N2流感疫苗在小鼠和雪貂中诱导出广泛的保护性免疫。

NPJ Vaccines. 2022 Jun 23;7(1):65. doi: 10.1038/s41541-022-00492-y.

A virus-like particle vaccination strategy expands its tolerance to H3N2 antigenic drift by enhancing neutralizing antibodies against hemagglutinin stalk.一种病毒样颗粒疫苗接种策略通过增强针对血凝素茎部的中和抗体来扩大其对H3N2抗原漂移的耐受性。

Antiviral Res. 2017 Apr;140:62-75. doi: 10.1016/j.antiviral.2017.01.010. Epub 2017 Jan 14.

Vaccination with whole inactivated virus vaccine affects the induction of heterosubtypic immunity against influenza virus A/H5N1 and immunodominance of virus-specific CD8+ T-cell responses in mice.接种全病毒灭活疫苗会影响小鼠对甲型流感病毒 A/H5N1 的异源免疫诱导和病毒特异性 CD8+ T 细胞应答的免疫优势。

J Gen Virol. 2010 Jul;91(Pt 7):1743-53. doi: 10.1099/vir.0.020784-0. Epub 2010 Mar 24.

Cell-Mediated Immunity Against Antigenically Drifted Influenza A(H3N2) Viruses in Children During a Vaccine Mismatch Season.疫苗不匹配季节儿童针对抗原性漂移甲型（H3N2）流感病毒的细胞介导免疫

J Infect Dis. 2016 Oct 1;214(7):1030-8. doi: 10.1093/infdis/jiw311. Epub 2016 Aug 17.

Human T-cells directed to seasonal influenza A virus cross-react with 2009 pandemic influenza A (H1N1) and swine-origin triple-reassortant H3N2 influenza viruses.针对季节性流感 A 病毒的人 T 细胞与 2009 年大流行流感 A（H1N1）和猪源三重重配 H3N2 流感病毒发生交叉反应。

J Gen Virol. 2013 Mar;94(Pt 3):583-592. doi: 10.1099/vir.0.048652-0. Epub 2012 Nov 14.

Bivalent H1 and H3 COBRA Recombinant Hemagglutinin Vaccines Elicit Seroprotective Antibodies against H1N1 and H3N2 Influenza Viruses from 2009 to 2019.二价 H1 和 H3 COBRA 重组血凝素疫苗可诱导针对 2009 年至 2019 年 H1N1 和 H3N2 流感病毒的血清保护性抗体。

J Virol. 2022 Apr 13;96(7):e0165221. doi: 10.1128/jvi.01652-21. Epub 2022 Mar 15.

Experimental PCEP-Adjuvanted Swine Influenza H1N1 Vaccine Induced Strong Immune Responses but Did Not Protect Piglets against Heterologous H3N2 Virus Challenge.实验性PCEP佐剂甲型H1N1流感疫苗诱导了强烈的免疫反应，但未能保护仔猪免受异源H3N2病毒攻击。

Vaccines (Basel). 2020 May 18;8(2):235. doi: 10.3390/vaccines8020235.

The European I-MOVE Multicentre 2013-2014 Case-Control Study. Homogeneous moderate influenza vaccine effectiveness against A(H1N1)pdm09 and heterogenous results by country against A(H3N2).欧洲2013 - 2014年I - MOVE多中心病例对照研究。针对甲型（H1N1）pdm09流感病毒，流感疫苗有效性表现出一致性且处于中等水平；而针对甲型（H3N2）流感病毒，不同国家的研究结果存在差异。

Vaccine. 2015 Jun 4;33(24):2813-22. doi: 10.1016/j.vaccine.2015.04.012. Epub 2015 Apr 28.

本文引用的文献

Advancing universal influenza vaccines: insights from cellular immunity targeting the conserved hemagglutinin stalk domain in humans.推进通用流感疫苗：针对人类保守血凝素茎区的细胞免疫研究见解

EBioMedicine. 2024 Jun;104:105172. doi: 10.1016/j.ebiom.2024.105172. Epub 2024 May 23.

Opportunities and challenges for T cell-based influenza vaccines.基于T细胞的流感疫苗的机遇与挑战。

Nat Rev Immunol. 2024 Oct;24(10):736-752. doi: 10.1038/s41577-024-01030-8. Epub 2024 May 2.

mRNA vaccines encoding computationally optimized hemagglutinin elicit protective antibodies against future antigenically drifted H1N1 and H3N2 influenza viruses isolated between 2018-2020.mRNA 疫苗编码经计算优化的血凝素，可诱导针对 2018-2020 年期间分离的未来抗原漂移的 H1N1 和 H3N2 流感病毒的保护性抗体。

Front Immunol. 2024 Mar 12;15:1334670. doi: 10.3389/fimmu.2024.1334670. eCollection 2024.

Increased genetic variation of A(H3N2) virus from influenza surveillance at the end of the 2016/2017 season for Shanghai port, China.中国上海港口 2016/2017 年流感监测末期 A(H3N2) 病毒遗传变异增加。

Sci Rep. 2022 Oct 12;12(1):17089. doi: 10.1038/s41598-022-19228-y.

Immunogenicity and Protective Efficacy of a Recombinant Pichinde Viral-Vectored Vaccine Expressing Influenza Virus Hemagglutinin Antigen in Pigs.表达流感病毒血凝素抗原的重组皮钦德病毒载体疫苗在猪体内的免疫原性和保护效力

Vaccines (Basel). 2022 Aug 26;10(9):1400. doi: 10.3390/vaccines10091400.

Efficacy and safety of a universal influenza A vaccine (MVA-NP+M1) in adults when given after seasonal quadrivalent influenza vaccine immunisation (FLU009): a phase 2b, randomised, double-blind trial.在季节性四价流感疫苗免疫接种（FLU009）后给予通用流感 A 疫苗（MVA-NP+M1）在成年人中的疗效和安全性：一项 2b 期、随机、双盲试验。

Lancet Infect Dis. 2022 Jun;22(6):857-866. doi: 10.1016/S1473-3099(21)00702-7. Epub 2022 Mar 16.

Role of γδ T cells in controlling viral infections with a focus on influenza virus: implications for designing novel therapeutic approaches.γδ T 细胞在控制病毒感染中的作用：以流感病毒为例——对设计新型治疗方法的启示。

Virol J. 2020 Nov 12;17(1):174. doi: 10.1186/s12985-020-01449-0.

Fifty Years of Influenza A(H3N2) Following the Pandemic of 1968.1968 年大流感后的五十年流感 A(H3N2)

Am J Public Health. 2020 May;110(5):669-676. doi: 10.2105/AJPH.2019.305557.

Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine.利用T细胞的力量：通用流感疫苗的光明前景。

Vaccines (Basel). 2018 Mar 26;6(2):18. doi: 10.3390/vaccines6020018.

Differences in clinical features between influenza A H1N1, A H3N2, and B in adult patients.成人患者中甲型H1N1流感、甲型H3N2流感和乙型流感临床特征的差异。

Respirology. 2003 Jun;8(2):231-3. doi: 10.1046/j.1440-1843.2003.00457.x.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验