Kim Janghwan, Kim Daesik, Seo Daeyun, Hwang Hyejin, Kim Yuna, Chung Taekyu, Lim Seongsoo, Lee Hansol, Kim Minsu, Park Seolgi, Youn Hwayoung
Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Gwanak-gu, Seoul, Republic of Korea.
Veterinary Internal Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Gwanak-gu, Seoul, Republic of Korea.
Vet Med (Praha). 2022 Feb 15;67(2):105-111. doi: 10.17221/155/2020-VETMED. eCollection 2022 Feb.
Surgical procedures on large skin defects can be challenging in the short term due to the size of the lesion, infection, and tissue defect. A regenerative therapy for skin wounds has been applied to promote the healing process. An 8-month-old, Korean domestic short-haired female cat, weighing 3 kg, was rescued with extensive defects on the right flank to right inguinal region caused by bite wounds. In this case, amniotic membranes and adipose-derived mesenchymal stem cells were used as the regenerative therapy to treat the large skin defect rather than a surgical intervention alone. To the best of our knowledge, this is the first report of a case with of a large skin defect treated by applying allogeneic amniotic membranes and allogeneic mesenchymal stem cells to a cat.
由于病变大小、感染和组织缺损等原因，短期内对大面积皮肤缺损进行外科手术具有挑战性。一种用于皮肤伤口的再生疗法已被应用于促进愈合过程。一只8个月大、体重3千克的韩国本土短毛雌性猫，因咬伤导致右侧胁腹至右腹股沟区域出现大面积缺损，被救了下来。在这个病例中，羊膜和脂肪来源的间充质干细胞被用作再生疗法来治疗大面积皮肤缺损，而不是仅进行外科干预。据我们所知，这是首例将同种异体羊膜和同种异体间充质干细胞应用于猫治疗大面积皮肤缺损的病例报告。
