Tiryaki Kemal Tunç, Canikyan Serli, Woods Jack, Sterodimas Aris, Gentile Pietro, Cohen Steven, Andjelkov Katarina, Schlaudraff Kai-Uwe, Siolo Eva, Kul Yaren, Duyan Ceren
From the Department of Plastic and Reconstructive Surgery, Cadogan Clinic, London, United Kingdom.
Department of Genetics and Bioengineering, Yeditepe University, Istanbul, Turkey.
Plast Reconstr Surg Glob Open. 2024 Aug 21;12(8):e6060. doi: 10.1097/GOX.0000000000006060. eCollection 2024 Aug.
Facial aging involves complex changes such as volume loss, ligament weakening, and skin quality alterations. The "two-thirds guidelines" emerge as a novel strategy to combat these aging signs, drawing from an extensive analysis of 2800 facial fat grafting procedures conducted over two decades.
Guided by facial lipolifting data, including patient age, fat type (microfat and nanofat), and injection depth, this study devises a systematic framework for multilayer fat rejuvenation and ligament restoration. The two-thirds guidelines advocate injecting two-thirds of the patient's age for microfat and one-third for nanofat, with specific injection codes for lower, middle, and upper facial regions.
A prospective study involving 400 patients confirms the efficacy of the two-thirds guidelines. However, applicability may vary for patients outside SD ranges, particularly concerning facial proportions and body mass index. Patients within the golden ratio range (1.4-1.9) report high satisfaction rates and a 50% fat graft uptake, with minimal complications. For patients outside this range, an artificial intelligence (AI) program was implemented.
The two-thirds guidelines offer a comprehensive approach to facial rejuvenation, addressing volume loss, ligament weakening, and skin quality. They are applicable in early aging stages, promising enduring and natural outcomes while mitigating effects of weight fluctuations. These guidelines provide a safe, replicable, and adaptable approach to facial fat grafting, either standalone or in combination with facelift techniques, with minimized overfilling risks. A dataset obtained from 2800 patients serves as the foundation for developing an AI program tailored to aid doctors in diagnosing and treating similar cases.
面部衰老涉及复杂的变化，如容积丧失、韧带松弛和皮肤质量改变。“三分之二法则”作为一种对抗这些衰老迹象的新策略应运而生，它源自对二十多年来2800例面部脂肪移植手术的广泛分析。
本研究以面部脂肪提升数据为指导，包括患者年龄、脂肪类型（微脂肪和纳米脂肪）及注射深度，设计了一个用于多层脂肪年轻化和韧带修复的系统框架。“三分之二法则”主张微脂肪注射量为患者年龄的三分之二，纳米脂肪为三分之一，并针对面部下、中、上区域制定了具体的注射编码。
一项涉及400例患者的前瞻性研究证实了“三分之二法则”的有效性。然而，对于标准差范围之外的患者，其适用性可能会有所不同，尤其是在面部比例和体重指数方面。处于黄金比例范围（1.4 - 1.9）内的患者报告满意度高，脂肪移植吸收率为50%，并发症极少。对于超出此范围的患者，则实施了人工智能（AI）程序。
“三分之二法则”为面部年轻化提供了一种全面的方法，可解决容积丧失、韧带松弛和皮肤质量问题。它们适用于早期衰老阶段，有望带来持久自然的效果，同时减轻体重波动的影响。这些法则为面部脂肪移植提供了一种安全、可重复且适应性强的方法，可单独使用或与面部提升技术联合使用，过度填充风险降至最低。从2800例患者获得的数据集为开发人工智能程序奠定了基础，该程序旨在帮助医生诊断和治疗类似病例。
