McMullen Eric P, Al Naser Yousif A, Maazi Mahan, Grewal Rajan S, Abdel Hafeez Dana, Folino Tia R, Vender Ronald B
Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Medical Radiation Sciences, McMaster University, Hamilton, ON, Canada.
Clin Exp Dermatol. 2025 Feb 24;50(3):520-528. doi: 10.1093/ced/llae348.
In dermatology, the applications of machine learning (ML), an artificial intelligence (AI) subset that enables machines to learn from experience, have progressed past the diagnosis and classification of skin lesions. A lack of systematic reviews exists to explore the role of ML in predicting the severity of psoriasis.
To identify and summarize the existing literature on predicting psoriasis severity using ML algorithms and to identify gaps in -current clinical applications of these tools.
OVID Embase, OVID MEDLINE, ACM Digital Library, Scopus and IEEE Xplore were searched from inception to August 2024.
In total, 30 articles met our inclusion criteria and were included in this review. One article used serum biomarkers, while the remaining 29 used image-based models. The most common severity assessment score employed by these ML models was the Psoriasis Area and Severity Index score, followed by body surface area, with 15 and 5 articles, respectively.
The small size and heterogeneity of the existing body of literature are the primary limitations of this review. Progress in assessing skin lesion severity through ML in dermatology has advanced, but prospective clinical applications remain limited. ML and AI promise to improve psoriasis management, especially in nonimage-based applications requiring further exploration. Large-scale prospective trials using diverse image datasets are necessary to evaluate and predict the clinical value of these predictive AI models.
在皮肤病学领域,机器学习(ML)作为人工智能(AI)的一个子集,能够使机器从经验中学习,其应用已超越皮肤病变的诊断和分类。目前缺乏系统性综述来探讨机器学习在预测银屑病严重程度方面的作用。
识别并总结使用机器学习算法预测银屑病严重程度的现有文献,并找出这些工具当前临床应用中的差距。
检索了从创刊至2024年8月的OVID Embase、OVID MEDLINE、ACM数字图书馆、Scopus和IEEE Xplore数据库。
共有30篇文章符合纳入标准并被纳入本综述。1篇文章使用血清生物标志物,其余29篇使用基于图像的模型。这些机器学习模型使用最频繁的严重程度评估分数是银屑病面积和严重程度指数分数,其次是体表面积,分别有15篇和5篇文章使用。
现有文献体量小且异质性大是本综述的主要局限。皮肤病学中通过机器学习评估皮肤病变严重程度已取得进展,但前瞻性临床应用仍然有限。机器学习和人工智能有望改善银屑病管理,尤其是在需要进一步探索的非基于图像的应用方面。有必要开展使用多样图像数据集的大规模前瞻性试验,以评估和预测这些预测性人工智能模型的临床价值。