Department of Pharmaceutical Chemistry, Faculty of Medicinal Chemistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Chair of Brewing and Beverage Technology, TUM School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
Adv Colloid Interface Sci. 2024 Oct;332:103277. doi: 10.1016/j.cis.2024.103277. Epub 2024 Aug 15.
The synthesis of nanoparticles (NPs) using environmentally friendly methods has garnered significant attention in response to concerns about the environmental impact of various nanomaterial manufacturing techniques. To address this issue, natural resources like extracts from plants, fungi, and bacteria are employed as a green alternative for nanoparticle synthesis. Plant extracts, which contain active components such as terpenoids, alkaloids, phenols, tannins, and vitamins, operate as coating and reducing agents. Bacteria and fungi, on the other hand, rely on internal enzymes, sugar molecules, membrane proteins, nicotinamide adenine dinucleotide (NADH), and nicotinamide adenine dinucleotide phosphate (NADPH) dependent enzymes to play critical roles as reducing agents. This review collects recent advancements in biomimetic methods for nanoparticle synthesis, critically discussing the preparation approaches, the type of particles obtained, and their envisaged applications. A specific focus is given on using Prosopis fractal plant extracts to synthesize nanoparticles tailored for biomedical applications. The applications of this plant and its role in the biomimetic manufacturing of nanoparticles have not been reported yet, making this review a pioneering and valuable contribution to the field.
使用环保方法合成纳米粒子(NPs)引起了人们的极大关注,因为人们担心各种纳米材料制造技术会对环境造成影响。为了解决这个问题,人们将植物、真菌和细菌等自然资源用作纳米颗粒合成的绿色替代品。植物提取物含有萜类化合物、生物碱、酚类、单宁和维生素等活性成分,可作为包覆和还原剂。另一方面,细菌和真菌依赖内部酶、糖分子、膜蛋白、烟酰胺腺嘌呤二核苷酸(NADH)和烟酰胺腺嘌呤二核苷酸磷酸(NADPH)依赖性酶作为还原剂发挥关键作用。本文综述了仿生法合成纳米粒子的最新进展,重点讨论了制备方法、获得的粒子类型及其预期应用。特别关注利用相思树植物提取物合成针对生物医学应用的纳米粒子。该植物的应用及其在纳米粒子仿生制造中的作用尚未有报道,因此,这篇综述对该领域是一个开拓性和有价值的贡献。