Weber Matthew P, Strobel Raymond J, Norman Anthony V, Kareddy Abhinav, Young Andrew, Young Steven, El Moheb Mohamad, Noona Sean W W, Wisniewski Alexander M, Quader Mohammed, Mazzeffi Michael, Yarboro Leora T, Teman Nicholas R
Division of Cardiothoracic Surgery, University of Virginia, Charlottesville, Va.
Department of Cardiac Surgery, Virginia Commonwealth University, Richmond, Va.
J Thorac Cardiovasc Surg. 2025 Apr;169(4):1271-1281. doi: 10.1016/j.jtcvs.2024.08.014. Epub 2024 Aug 22.
The impact of Cardiac Surgical Unit-Advanced Life Support (CSU-ALS) training on failure to rescue after cardiac arrest (FTR-CA) is unknown. We hypothesized that institutional CSU-ALS certification would be associated with lower FTR-CA.
Patients undergoing Society of Thoracic Surgeons index operations from 2020 to 2023 from a regional collaborative were analyzed. Each institution was surveyed regarding its status as a CSU-ALS-certified center. Patients stratified by CSU-ALS certification were 1:1 propensity score matched with subsequent multivariable model reviewing associations with FTR-CA.
A total of 12,209 patients were included in the study period across 15 institutions. Eight centers reported CSU-ALS certification. After propensity score matching, 2 patient cohorts were formed (n = 3557). Patients at CSU-ALS centers had greater rates of intensive care unit readmission (3.9% vs 2.3%, P < .01) and total operating room time (340 minutes vs 323 minutes, P < .01). Hospital readmission was less likely in the CSU-ALS centers (9.0% vs 10.1%, P < .01). There was no difference in the rate of postoperative cardiac arrest (1.8% vs 2.2%, P = .24) or operative mortality (2.5% vs 2.9%, P = .30). After risk adjustment, CSU-ALS centers (odds ratio, 0.30; 95% confidence interval, 0.12-0.72, P < .01) and greater-volume centers (odds ratio, 0.15; confidence interval, 0.03-0.74, P = .02) had reduced odds of FTR-CA.
Centers with CSU-ALS certification are associated with a lower risk-adjusted likelihood of FTR-CA. This highlights the importance of well-trained staff and treatment algorithms in the care of patients postcardiac surgery.
心脏外科单元高级生命支持(CSU-ALS)培训对心脏骤停后抢救失败(FTR-CA)的影响尚不清楚。我们假设机构CSU-ALS认证与较低的FTR-CA相关。
对2020年至2023年在一个区域协作中接受胸外科医师协会索引手术的患者进行分析。就每个机构作为CSU-ALS认证中心的状况进行调查。按CSU-ALS认证分层的患者进行1:1倾向评分匹配,随后进行多变量模型分析与FTR-CA的关联。
在研究期间,15个机构共有12209例患者纳入研究。8个中心报告了CSU-ALS认证。倾向评分匹配后,形成了2个患者队列(n = 3557)。CSU-ALS中心的患者重症监护病房再入院率更高(3.9%对2.3%,P <.01),总手术室时间更长(340分钟对323分钟,P <.01)。CSU-ALS中心的医院再入院可能性较小(9.0%对10.1%,P <.01)。术后心脏骤停发生率(1.8%对2.2%,P =.24)或手术死亡率(2.5%对2.9%,P =.30)没有差异。风险调整后,CSU-ALS中心(比值比,0.30;95%置信区间,0.12 - 0.72,P <.01)和手术量较大的中心(比值比,0.15;置信区间,0.03 - 0.74,P =.02)的FTR-CA几率降低。
具有CSU-ALS认证的中心与经风险调整后较低的FTR-CA可能性相关。这突出了训练有素的工作人员和治疗算法在心脏手术后患者护理中的重要性。