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体外生命支持组织卓越中心的认可与心脏骤停后抢救失败的改善有关。

Extracorporeal Life Support Organization Center of Excellence recognition is associated with improved failure to rescue after cardiac arrest.

机构信息

Division of Cardiac Surgery, Department of Surgery, University of Virginia, Charlottesville, Va.

School of Medicine, University of Virginia, Charlottesville, Va.

出版信息

J Thorac Cardiovasc Surg. 2024 May;167(5):1866-1877.e1. doi: 10.1016/j.jtcvs.2023.04.031. Epub 2023 May 6.

Abstract

OBJECTIVE

The influence of Extracorporeal Life Support Organization (ELSO) center of excellence (CoE) recognition on failure to rescue after cardiac surgery is unknown. We hypothesized that ELSO CoE would be associated with improved failure to rescue.

METHODS

Patients undergoing a Society of Thoracic Surgeons index operation in a regional collaborative (2011-2021) were included. Patients were stratified by whether or not their operation was performed at an ELSO CoE. Hierarchical logistic regression analyzed the association between ELSO CoE recognition and failure to rescue.

RESULTS

A total of 43,641 patients were included across 17 centers. In total, 807 developed cardiac arrest with 444 (55%) experiencing failure to rescue after cardiac arrest. Three centers received ELSO CoE recognition, and accounted for 4238 patients (9.71%). Before adjustment, operative mortality was equivalent between ELSO CoE and non-ELSO CoE centers (2.08% vs 2.36%; P = .25), as was the rate of any complication (34.5% vs 33.8%; P = .35) and cardiac arrest (1.49% vs 1.89%; P = .07). After adjustment, patients undergoing surgery at an ELSO CoE facility were observed to have 44% decreased odds of failure to rescue after cardiac arrest, relative to patients at non-ELSO CoE facility (odds ratio, 0.56; 95% CI, 0.316-0.993; P = .047).

CONCLUSIONS

ELSO CoE status is associated with improved failure to rescue following cardiac arrest for patients undergoing cardiac surgery. These findings highlight the important role that comprehensive quality programs serve in improving perioperative outcomes in cardiac surgery.

摘要

目的

体外生命支持组织(ELSO)卓越中心(CoE)的认可对心脏手术后的抢救失败的影响尚不清楚。我们假设 ELSO CoE 将与抢救成功率的提高相关。

方法

纳入在区域合作(2011-2021 年)中进行胸外科协会指数手术的患者。根据其手术是否在 ELSO CoE 进行,将患者分为不同的亚组。使用分层逻辑回归分析 ELSO CoE 认可与抢救失败之间的关系。

结果

共有 17 个中心的 43641 名患者纳入研究。共有 807 名患者发生心脏骤停,其中 444 名(55%)在心脏骤停后抢救失败。有 3 个中心获得了 ELSO CoE 的认可,共涉及 4238 名患者(9.71%)。在调整之前,ELSO CoE 中心和非 ELSO CoE 中心的手术死亡率相当(2.08%比 2.36%;P=0.25),任何并发症的发生率(34.5%比 33.8%;P=0.35)和心脏骤停发生率(1.49%比 1.89%;P=0.07)也相当。调整后,与非 ELSO CoE 中心相比,在 ELSO CoE 中心接受手术的患者,发生心脏骤停后抢救失败的可能性降低了 44%(优势比,0.56;95%置信区间,0.316-0.993;P=0.047)。

结论

ELSO CoE 状态与心脏手术后心脏骤停患者抢救失败率降低相关。这些发现强调了全面质量计划在改善心脏手术围手术期结局方面的重要作用。

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