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多病症对中国老年成年人抑郁状况的影响:来自中国健康与养老追踪调查(CHARLS)的证据。

Effect of multimorbidity on depressive status in older Chinese adults: evidence from the China Health and Retirement Longitudinal Study (CHARLS).

机构信息

Department of General Practice, Zhejiang University School of Medicine, Sir Run Run Shaw Hospital, Hangzhou, China

Department of General Practice, Zhejiang University School of Medicine, Sir Run Run Shaw Hospital, Hangzhou, China.

出版信息

BMJ Open. 2024 Aug 21;14(8):e081776. doi: 10.1136/bmjopen-2023-081776.

Abstract

OBJECTIVE

This study aims to further explore the relevant influencing factors of depression and explore the correlation between multimorbidity coexistence and depression to find the goals and methods of early intervention of depression in the elderly.

DESIGN

This study adopts a cross-sectional approach.

SETTING

The study population of this project came from the China Health and Retirement Longitudinal Study. Depression was grouped according to the 10-item version of Centre for Epidemiological Research Depression Scale. Chronic diseases, height, weight, grip strength, education, marital status, alcohol consumption, exercise and other indicators were included in the analysis.

PARTICIPANTS

2239 adults over 60 years of age were included.

RESULTS

The proportion of women in the depression group was higher (p<0.001). The depression group had a lower grip strength than the control group (p<0.05). The sleep duration was shorter in the depression group (p<0.001). There were differences in education, marital status and alcohol consumption in the depression group (p<0.05). The depression group might have more types of coexisting chronic diseases (p<0.001). The depression group was more likely to have hypertension, dyslipidaemia, chronic lung diseases, heart attack, stroke, stomach disease and memory-related disease. Grip strength was connected with the risk of depression in the elderly (0.971 (95% CI 0.959 to 0.984)). Sleep (0.827 (95% CI 0.785 to 0.872) and education level (0.790 (95% CI 0.662 to 0.942) were related to the risk of depression in the elderly. Concomitant chronic diseases could affect the risk of depression in the elderly (1.455 (95% CI 1.243 to 1.703)).

CONCLUSION

The coexistence of multiple chronic diseases and depression is very common in the elderly. The coexistence of multiple chronic diseases is more common in older women and older depressed people. With the increase in the number of chronic diseases, the risk of depression in the elderly is significantly increased.

摘要

目的

本研究旨在进一步探讨抑郁的相关影响因素,并探讨多种共存疾病与抑郁之间的相关性,以寻找老年人抑郁的早期干预目标和方法。

设计

本研究采用横断面研究设计。

地点

本项目的研究人群来自中国健康与养老追踪调查。根据流行病学研究抑郁量表的 10 项版本将抑郁进行分组。将慢性疾病、身高、体重、握力、教育程度、婚姻状况、饮酒、运动等指标纳入分析。

参与者

共纳入 2239 名 60 岁以上的成年人。

结果

抑郁组女性比例较高(p<0.001)。抑郁组握力低于对照组(p<0.05)。抑郁组的睡眠时间较短(p<0.001)。抑郁组在教育程度、婚姻状况和饮酒方面存在差异(p<0.05)。抑郁组可能存在更多种共存的慢性疾病(p<0.001)。抑郁组更易患有高血压、血脂异常、慢性肺部疾病、心脏病发作、中风、胃病和记忆相关疾病。握力与老年人患抑郁的风险相关(0.971(95%CI 0.959 至 0.984))。睡眠(0.827(95%CI 0.785 至 0.872))和教育程度(0.790(95%CI 0.662 至 0.942))与老年人患抑郁的风险相关。共存的慢性疾病会影响老年人患抑郁的风险(1.455(95%CI 1.243 至 1.703))。

结论

多种共存慢性疾病和抑郁在老年人中非常常见。多种共存慢性疾病在老年女性和老年抑郁患者中更为常见。随着慢性疾病数量的增加,老年人患抑郁的风险显著增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684b/11340719/7ef0c06ea9c1/bmjopen-14-8-g001.jpg

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