Vanke School of Public Health, Tsinghua University, Beijing, China.
Institute for Healthy China, Tsinghua University, Beijing, China.
Epidemiol Psychiatr Sci. 2022 Sep 8;31:e63. doi: 10.1017/S2045796022000452.
To assess the association of sleep factors (sleep duration, trouble sleeping, sleep disorder) and combined sleep behaviours with the risk of clinically relevant depression (CRD).
A total of 17 859 participants (8806 males and 9053 females) aged 20-79 years from the National Health and Nutrition Examination Survey (NHANES) 2007-2014 waves were included. Sleep duration, trouble sleeping and sleep disorder were asked in the home by trained interviewers using the Computer-Assisted Personal Interviewing (CAPI) system. The combined sleep behaviours were referred to as 'sleep patterns (healthy, intermediate and poor)', with a 'healthy sleep pattern' defined as sleeping 7-9 h per night with no self-reported trouble sleeping or sleep disorders. And intermediate and poor sleep patterns indicated 1 and 2-3 sleep problems, respectively. Weighted logistic regression was performed to evaluate the association of sleep factors and sleep patterns with the risk of depressive symptoms.
The total prevalence of CRD was 9.5% among the 17 859 participants analysed, with females having almost twice as frequency than males. Compared to normal sleep duration (7-9 h), both short and long sleep duration were linked with a higher risk of CRD (short sleep: OR: 1.66, 95% CI: 1.39-1.98; long sleep: OR: 2.75, 95% CI: 1.93-3.92). The self-reported sleep complaints, whether trouble sleeping or sleep disorder, were significantly related with CRD (trouble sleeping: OR: 3.04, 95% CI: 2.59-3.56; sleep disorder: OR: 1.83, 95% CI: 1.44-2.34). Furthermore, the correlations appeared to be higher for individuals with poor sleep pattern (OR: 5.98, 95% CI: 4.91-7.29).
In this national representative survey, it was shown that there was a dose-response relationship between sleep patterns and CRD.
评估睡眠因素（睡眠时间、睡眠障碍、睡眠障碍）和综合睡眠行为与临床相关抑郁（CRD）风险的关联。
共纳入来自 2007-2014 年全国健康和营养调查（NHANES）的 17859 名年龄在 20-79 岁的参与者（男性 8806 名，女性 9053 名）。睡眠持续时间、睡眠障碍和睡眠障碍由经过培训的访谈员使用计算机辅助个人访谈（CAPI）系统在家庭中询问。综合睡眠行为被称为“睡眠模式（健康、中间和差）”，“健康睡眠模式”定义为每晚睡眠 7-9 小时，无自我报告的睡眠障碍或睡眠障碍。中间和较差的睡眠模式分别表示存在 1 个和 2-3 个睡眠问题。采用加权 logistic 回归评估睡眠因素和睡眠模式与抑郁症状风险的关系。
在所分析的 17859 名参与者中，CRD 的总患病率为 9.5%，女性的患病率几乎是男性的两倍。与正常睡眠时间（7-9 小时）相比，短睡眠和长睡眠均与 CRD 风险增加相关（短睡眠：OR：1.66，95%CI：1.39-1.98；长睡眠：OR：2.75，95%CI：1.93-3.92）。自我报告的睡眠问题，无论是睡眠障碍还是睡眠障碍，与 CRD 明显相关（睡眠障碍：OR：3.04，95%CI：2.59-3.56；睡眠障碍：OR：1.83，95%CI：1.44-2.34）。此外，对于睡眠模式较差的个体，相关性似乎更高（OR：5.98，95%CI：4.91-7.29）。
在这项具有全国代表性的调查中，表明睡眠模式与 CRD 之间存在剂量-反应关系。
