腹腔镜袖状胃切除术后四肢骨骼肌质量变化与体重减轻及内脏脂肪减少的关联
Association of changes in appendicular skeletal muscle mass with weight loss and visceral fat reduction after laparoscopic sleeve gastrectomy.
作者信息
Uno Kohei, Sato Kazuhide, Watanabe Atsushi, Kudo Tomohiro, Fukushima Naoko, Takahashi Keita, Masuda Takahiro, Kurogochi Takanori, Yuda Masami, Yano Fumiaki, Eto Ken
机构信息
Department of Surgery, Jikei University School of Medicine, 3-19-18 Nishishimbashi , Minato-ku, Tokyo, 105-8471, Japan.
Department of Surgery, Saitama Jikei Hospital, 3-208 Ishihara, Kumagayashi, Saitama, 360-0816, Japan.
出版信息
Surg Today. 2025 Mar;55(3):434-441. doi: 10.1007/s00595-024-02925-8. Epub 2024 Aug 22.
PURPOSE
Laparoscopic sleeve gastrectomy (LSG) drastically affects body composition. However, studies focusing on the association between the changes in the pre-and postoperative muscle mass and postoperative results are limited. We evaluated the association between changes in the muscle mass and weight loss and fat reduction.
METHODS
This retrospective study included 29 consecutive patients who underwent both LSG and a bioelectrical impedance analysis (BIA) consecutively. We investigated changes in the body composition on the BIA and visceral fat area (VFA) on computed tomography and correlational changes in muscle mass with weight loss and fat reduction.
RESULTS
The total weight loss (%TWL) 12 months after surgery was 30.9%. The VFAs pre- and postoperatively were 224 and 71.0 cm, respectively. The fat mass (FM), percentage of FM, appendicular skeletal muscle mass (ASM), and skeletal muscle mass index (SMI) decreased from pre- to postoperatively (54.8 vs. 32.2 kg; 49.0 vs. 41.2%, 26.7 vs. 23.9 kg, 9.24 vs. 8.27, respectively), whereas the percentage of ASM (%ASM) increased (22.1 vs. 28.0%). The rate of change in %ASM positively correlated with weight loss and fat reduction (%TWL, rs = 0.65; %VFA loss, rs = 0.62).
CONCLUSION
The rate of change in %ASM was positively correlated with weight loss and fat reduction.
目的
腹腔镜袖状胃切除术（LSG）会极大地影响身体组成。然而，关注术前和术后肌肉量变化与术后结果之间关联的研究有限。我们评估了肌肉量变化与体重减轻及脂肪减少之间的关联。
方法
这项回顾性研究纳入了29例连续接受LSG和生物电阻抗分析（BIA）的患者。我们通过BIA研究身体组成的变化以及通过计算机断层扫描研究内脏脂肪面积（VFA），并研究肌肉量与体重减轻和脂肪减少的相关变化。
结果
术后12个月的总体重减轻率（%TWL）为30.9%。术前和术后的VFA分别为224和71.0平方厘米。脂肪量（FM）、FM百分比、四肢骨骼肌量（ASM）和骨骼肌量指数（SMI）从术前到术后均下降（分别为54.8对32.2千克；49.0对41.2%，26.7对23.9千克，9.24对8.27），而ASM百分比（%ASM）增加（22.1对28.0%）。%ASM的变化率与体重减轻和脂肪减少呈正相关（%TWL，rs = 0.65；%VFA减少，rs = 0.62）。
结论
%ASM的变化率与体重减轻和脂肪减少呈正相关。
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